【製品名(商品名)】
曽我山みかん
【種類】
Citrus L.
【生産地】
神奈川県小田原市曽我大沢(杉崎農場)
【名前の由来】
From Odawara / Mt. Soga, which is full of light and greenery
【主な特徴】
“Odawara City, Kanagawa Prefecture”, Developed as a "castle town" of Mr. Gohojo(Soun Hojo-Ko is the ancestor)during the Warring States period.During the Edo period, it prospered as one of the best "Post Towns" on the Tokaido.Political and business people and cultural people:Center City in the western region, which has been loved as a villa, a place of residence- Meiji Period.Green mountains, clear rivers, magnificent seas, fertile plains.And the warm climate is wonderful.The long history, traditions and culture built by many ancestors.It is also blessed with a warm and mild climate and abundant water.Agriculture is rice cultivation in the paddy fields that spread over the Sakawa River basin that runs through the center of the city:A longevity village that boasts greenery and historical heritage and looks up at Mt. Fuji:It is roughly divided into fruit trees mainly composed of Citrus in the orchard found in the Soga hills in the east.It grows at the foot of Mt. Hakone, which extends from the south to the west.In addition, livestock farming is flourishing in the eastern and Shimonaka(Onion:Climatic conditions such as the temperature difference between day and night and the sea breeze blowing from Sagami Bay.Suitable for growing sweet and delicious onions.It uses abundant cow dung compost grown by local livestock farmers and contains organic substances- Soil)districts.Major agricultural and livestock products:The number one agricultural output is mandarin oranges with a cultivated area of 546 ha.In recent years, mandarin orange production has been on a downward trend due to price instability.In addition, the conversion of paddy fields and the accompanying decrease in agricultural workers.Rice is decreasing year by year due to demand adjustment by Japan's measures.For orange gardens, go to kiwifruit and plum trees, and for paddy fields, vegetables, strawberries, flowers, etc- Conversion.Therefore, the number of farmers aiming for independent management through intensive cultivation is increasing.In the deciduous fruit tree, plum tree has been cultivated for a long time mainly in the Soga Area as a special product.‘Pear’ is cultivated mainly in the Sakawa River basin.Land infrastructure development project:In the future, it is expected to develop as a tourism business in combination with the development of the Road Network.Furthermore, increasing the added value of local agricultural products and we are aiming to eliminate idle farmland.Agricultural entry by agricultural legal persons, Co., Ltd., NPO corporations, etc.PR of agricultural products by developing special products such as Odawara Wine series.Efforts to improve the brand of Odawara- Juro Plum(Currently, the main production area is from Odawara to Ashigarakami Area.Plum cultivation has a history of more than 500 years.Kanagawa Prefecture Agricultural Experiment Station Horticulture Department:Selected from native seedlings in Ashigarakami District.Named by the city's Plum Study Group in 1960.The flowering period is particularly early, and the fruits tend to be oval, small and thin.The flesh is good, the flesh ratio is high, and it turns yellow as it ripens.The best dried plum varieties, harvested in mid-late June.)and ‘Shonan Gold’.Agriculture unique to the city develops.In recent years, the shortage of farmers' successors and the aging of the population have become more serious.Wild boars(Sus scrofa Linnaeus, 1758)settle in the devastated land, and the surrounding mandarin orange gardens are damaged.There is also a vicious cycle of further expansion of abandoned cultivated land and devastated land.Furthermore, the mountain that has lost its utility value loses human involvement.Bamboo grove due to the invasion of Moso bamboo(Phyllostachys heterocycla f. pubescens)/ Weeds grow thick and trees begin to die due to lack of sunlight.Vegetational change:A state where the mountain is left unattended while repeating:If it continues, it could change the Animal Ecosystem.Satoyama landscapes are by no means natural.This issue requires sustainable conservation and rehabilitation work by humans.I am concerned that the number of Abandoned cultivated lands in mandarin orange gardens is increasing in the soga- osawa area.It's the same as the 6th generation of Sugizaki Farm is worried.He rented an adjacent 1000 km2, felled trees and practiced clearing.Then, from 2017, 117 very early oranges were planted.The variety is “Yura-Wase”, which has good coloring and high sugar content.Put the varieties harvested from November to December in a wooden box.On the farm, it has been passed down and cherished for generations.Then, it is stored in the clay wall warehouse before shipping;Earth wall storage mandarin orange.In recent years, changes in climate and consumer lifestyles have occurred.Introducing new varieties that can be harvested and shipped immediately from October to November.I've been quick to do this.It seems that it will take about five years to harvest new varieties in the adjacent land.Proceeding from that time to now will lead to stabilization of the future production system.There are storages, each of which is used by taking advantage of the characteristics and environment of the hut.After harvesting, it is stored on the clay wall by pulling out and stacking.The acidity becomes mellow, the sweetness increases, and the inner bag becomes soft.No herbicides- Soil power, In order to make the best use of it, we are particular about cultivating grass.People mow the grass that has grown.Then, the cut grass becomes fertilizer and nutrients for the tree.Terraced fields are scattered in the soil called the lexic clay layer.Stepped terraced fields:Suitable for making mandarin orange in a sunny and well-drained field.In addition, this is a terrain that receives a lot of sunshine from Mt. Hakone in the evening- “Sunset”.In a warm mandarin field, we have been making mandarin oranges for generations since the Edo period.The blessed land is a gift of Ancestors and Local residents.Soil fish meal fertilizer or Rapeseed meal fertilizer etc., We give plenty of nutritious fertilizer to make something with a strong taste.Harvesting operation efficiency:It is transported using monorails and crawlers.In addition, there is a large mandarin orange sorting machine on the farm.Sorted and boxed on the farm and shipped individually.From early October to mid-March (shipping time varies depending on the year)
【栄養素・機能性成分】
βカロテン:C40H56;Converted to vitamin A in the body as needed.Carotenoids that are abundant in green and yellow vegetables.It is important for maintaining the health of skin and mucous membranes and for photostimulatory response, and promotes cell proliferation.
ビタミンB1;Decarbonization in the ketoglutarate dehydrogenase reaction:Coenzyme;Form of thiamine pyrophosphate.
B2;The form of flavin adenine dinucleotide as a cofactor for the α-ketoglutarate dehydrogenase complex and succinate dehydrogenase.
B6;Pyridoxine(C8H11NO3), Pyridoxal(C8H9NO3), Pyridoxiamine(C8H12N2O2);Coenzyme for protein, lipid and carbohydrate metabolism:It acts as a coenzyme(Pyridoxal phosphate)for metabolism of bioactive amines, which is a neurotransmitter, and as a hormone regulator:Helps keep nerves and skin healthy, fight infections, keep blood sugar levels normal, produce red blood cells, and some enzymes work properly.
パントテン酸(Cofactor fused with active carboxylic acid residues such as Acyl coa and succinyl-coa:Coenzyme A(Cysteamine):C21H36P3N7O16S)
ナイアシン(The form of nicotinamide adenine dinucleotide as a coenzyme of isocitrate dehydrogenase, α-ketotoglutarate dehydrogenase, malate dehydrogenase.)
ビオチン(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid:C10H16N2O3S):ビタミンH;It is a colorless acicular crystal that is stable to neutral, acidic, alkaline, oxygen, and light, but weak to heat.It is released from proteins in food by biotinidase(dominant gene)secreted by the pancreas.It translocates into the blood and binds to biotinidase, a transport protein synthesized in the liver.
葉酸;ビタミンM(2S)-2-[(4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid:C19H19N7O6;Pteridine(C6H4N4)with para-aminobenzoic acid; PABA(C7H7NO2)and another or more glutamic acids.Most exist in the "Polyglutamic acid type" (A combination of multiple glutamic acids).I heard that it is absorbed from the epithelial cells of the small intestine after being converted to the "Monoglutamic acid type" (A form in which one glutamic acid is bound) by digestive enzymes in the digestive tract.It is soluble in acids and alkalis, but hardly soluble in pure water or ethanol, and tends to be insoluble in acetone(C3H6O),Diethyl ether((C2H5)2O), Chloroform(CHCl3), and Benzene(C6H6).In the polyglutamic acid type folate, sugar and protein are released and released in the cooking and processing of foods and in the gastric acid environment.It is decomposed into monoglutamic acid-type folic acid by an enzyme in the small intestinal mucosa and then absorbed into the cells of the small intestine.I heard that it is converted to 5-methyltetrahydrofolic acid by the enzyme(small intestinal epithelial cell).It is transported to the liver via the portal vein, and 50% of the whole body seems to accumulate.It is converted again and transferred to bile, which is reabsorbed from the digestive tract and supplied to tissues for transfer.It is required to return homocysteine, a risk factor for arteriosclerosis, to methionine.etc.
ビタミンC:C6H8O6;Discovered as a Skorbut preventive factor by Royal Navy doctor James Lind in 1753.It removes rust from water-soluble parts of the body, such as blood and the crystalline lens of the eye, and also restores tired vitamin E.It is absorbed mainly from the small intestine as it is without being digested by the stomach. It is then carried in the blood, stored and dispersed throughout the body.It is characterized by its "antioxidant effect", which inhales, captures a small amount of active oxygen obtained, and detoxifies it.Excessive growth damages DNA or Protein and reduces cell function.
ビタミンE:C29H50O2;It is divided into a total of eight compounds, four tocopherols(In nature, α, β, γ, δ.)and four tocotrienols.It is absorbed into the body from the intestinal tract via the lymphatic vessels together with lipids, and has a very strong antioxidant effect.Protects unsaturated fatty acids and other fat-soluble components that make up biological membranes from oxidative damage:Included in the phospholipid bilayer of cell membranes.It suppresses the production of lipid peroxide, keeps blood vessels healthy, and suppresses the oxidation of LDL(Bad cholesterol)cholesterol in the blood.You will not have hypervitaminosis with a normal diet, as you tend not to have cumulative actions in your body.
βクリプトキサンチン:Provitamin A:C40H56O:Ester body, carotenoid.It forms mixed micelles with bile acids, fatty acids, cholesterol, etc., and is passively diffused and absorbed by small intestinal epithelial cells.Move to liver with chylomicron(Lipoprotein particles;乳糜脂粒).Very low density lipoprotein and “Low-Density Lipoprotein Cholesterol”:To peripheral tissues≒Ester body.
ビオラキサンチン:(1S,4S,6R)-1-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4S,6R)-4-Hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-4-ol;C40H56O4:The gene expression balance is clear, which makes it difficult to accumulate BCR(Caricaxanthin)and facilitates the accumulation of more metabolized VIO(Carotenoid).It is considered as a precursor of a plant hormone called "abscisic acid(C15H20O4)" that promotes leaf fall.
ペクチン:methyl ester:J.Braconnot,1825(Rf):Galacturonic acid:carboxyl group:-C(=O)OH
セルロース:(C6H10O5)n;The main component of plant cell sell stones and plant fibers, and the most abundant carbohydrate on earth.
ヘミセルロース(Amyloid):Discovered by E. Schulze in 1891.The name of the polysaccharide extracted with alkali after extracting Pectin from cell wall carbohydrates.Xyloglucan(Angiospermae):With 1,4-β-D-glucan as the main chain, the α-D-xylose residue binds to the O-6 position of the D-glucose residue of 75%.It is distributed throughout the cell wall including the middle lobe, and I hear that it is hydrogen-bonded to cellulose.Tendency to exist as a storage polysaccharide in seeds.
リグニン:Sphingomonas paucimobilis SYK-6:bacterium:Mineralization;Effective resistance to decay and feeding damage.
ビタミンP:ヘスペリジン;flavonoid:C28H34O15:polyphenol;Glycotransfer works in cooperation with vitamin C to regulate the permeability of the capillary membrane so that it does not become too permeable.
ルチン;C27H30O16:β-rutinose((2R,3S,4S,5S)-6-[ [(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxane-2,3,4,5-tetrol;C12H22O10)bound to quercetin.The E-rutin group significantly increased muscle weight and lean weight in the lower limbs compared to the placebo group that ingested E-rutin-free whey protein-n = 1, isoquercitrin;C21H20O12.Research results increase potential antioxidants in the blood.It protects cells and tissues by suppressing or eliminating the generation of reactive oxygen species, and preserves the normal normality and growth of muscles.etc.
ネオヘスペリジン:C28H34O15
シネフリン:4-[1-hydroxy-2-(methylamino)ethyl]phenol:C9H13NO2;Used in various slimming natural health products as an alternative to the pharmaceutical ingredient ephedrine.It has effects on heart rate and blood pressure, and both pharmacological effects tend to be significantly enhanced by caffeine.From the identified risk.
オーラプテン:auraptene,7-geranyloxycoumarin:C19H22O3
テルペノイド:aldehyde,carboxylic acid:C5:IPP,DMAPP:C10, C15, C20:prenyltransferase
ナリンギン:flavanone:C27H32O14;A glycoside in which a sugar called Neo hesperidos is bound to naringenin.When hydrolyzed with the degrading enzyme naringinase, it changes to naringenin without bitterness, so it is often used for fruit juice processing.
クエン酸:C(OH)(CH2COOH)2COOH:C6H8O7;When energy is taken up by the living body, it decomposes through various processes to become a substance called acetyl-coa (active acetic acid), which binds to Oxaloacetic acid(C4H4O5).Later, it transforms into seven types of acids and returns to citric acid.TCA cycle:A substance called "ATP (adenosine triphosphate(C10H16N5O13P3))" that acts as an energy source for cells in the body.Effective against lactic acid, which is the source of stiff shoulders and muscle fatigue.
ブドウ糖:C6H12O6:D-グルコース:Known as a component of cellulose, starch and glycogen.D-glucose(Dextrose, an organic compound.)and pure crystalline monosaccharides produced after the starch is completely hydrolyzed.It is divided into water-containing water containing molecular water of crystallization and anhydrous water containing nothing.
酒石酸:2,3-dihydroxy butanedioic acid:(CH(OH)COOH)2:L-(+)-Tartaric acid:It is known as a crystalline organic acid obtained by oxidizing and enzymatically decomposing maleic acid(HOOC–CH=CH–COOH:Chain unsaturated dicarboxylic acid)or fumaric acid(HOOC–CH=CH–COOH:C4H4O4:-2-ブテン二酸:Alpha hydroxy acid).
リンゴ酸:HOOC-CH(OH)-CH2-COOH:C4H6O5;2-hydroxybutanedioic acid;It is known as an organic acid obtained by synthesizing fumaric acid or reducing glucose.Dicarboxylic acid, in the role of an intermediate in the TCA cycle:Alpha hydroxy acid.
ケンフェロール:C15H10O6
(+)カテキン:C15H14O6;Flavonoids of polyphenols.Derived from the dark brown "catechu" taken from the Acacia Mill. / Acacia (Fabaceae) trees that grow in India.There are research cases that eliminate infectivity by adhering to protruding proteins on the surface such as influenza virus.
イソロイシン(C6H13NO2:2-アミノ-3-メチルペンタン酸);Hydrophobic amino acid(BCCA).The role of promoting the uptake of blood glucose into skeletal muscle without an increase in blood sugar concentration.It works to suppress gluconeogenesis(A pathway that slowly reverses glycolysis from lactic acid, pyruvic acid, amino acid, propionic acid, etc. to produce D-glucose.)in the liver and to oxidatively utilize glucose.A zwitterionic compound having a leucine structural isomer and a sec-butyl group (-ch (ch3) ch2ch3) in the side chain.
ロイシン(C6H13NO2:2-Amino-4-methylpentanoic acid);Activator of mTOR:mammallian Target Of Rapamycin(Atypical serine-threonine kinases present in two types of complexes:It senses nutrient sources such as glucose and amino acid, and plays a role of regulators in cell proliferation, metabolism, and survival.):There are insulin, IGF-1 (insulin-like growth factor 1: insulin-like growth factors 1), Testosterone, Nitric oxide, Muscle Contraction etc.An important factor that promotes protein synthesis(BCCA).
リシン(リジン:C6H14N2O2:2,6-diaminohexanoic acid);It is known as a synthetic raw material for carnitine(C7H15NO3:Derivative)required for fat burning.In the human body, we also hear examples of promotion of glucose metabolism and its relationship with calcium absorption.L-Lysine Hydrochloride:Mol fileKCF fileDB search(HCl:hydrochloric acid).
(含硫)メチオニン(C5H11NO2S:2-amino-4-(methylthio)butanoic acid);It is a sulfur-containing amino acid containing sulfur and is converted into glutathione(C10H17N3O6S)and taurine(C2H7NO3S)in the body.It is also known as a biosynthetic raw material for carnitine involved in fat burning.Tendency to be metabolized in a series of reactions called carbon metabolism.Using methionine and ATP synthase as substrates, S-adenosylmethionine synthase catalyzes the biosynthesis of S-adenosylmethionine(C15H22N6O5S+):Protein methylation.
シスチン( C6H12N2O4S2:2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid);The role of stabilizing the structure of Proteins.It is one of the sulfur-containing amino acids(The composition of Glutathione-SH(C10H17N3O6S), which is important for detoxification and antioxidant activity.)containing sulfur and has a unique aroma.It converts methionine to Cystathionine(C7H14N2O4S:A catalyst for β-synthase from Homocysteine(C4H9NO2S:2-Amino-4-sulfanylbutanoic acid)and Serine.)in the human body.It is famous as a sulfur-containing amino acid in which two molecules of cysteine are bound.
(芳香族)フェニルアラニン( C9H11NO2:2-Amino-3-phenylpropanoic acid);In the brain, the role of Synthesizing Neurotransmitter Norepinephrine(C8H11NO3:4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol;Monoamine(A chemical structure in which an amino group is connected to an aromatic ring by two carbon chains.))and Dopamine(C8H11NO2:Monoamine neurotransmitter).It is also known as a raw material for Tyrosine(C9H11NO3:4-hydroxyphenylalanine;Protein production synthesis).Important for accelerating the amyloid assembly process.Adrenaline(Adrenal medulla):Epinephrine(C9H13NO3),Produced by neurons and released as adrenal medulla hormones and neurotransmitters.
チロシン(C9H11NO3:2-Amino-3-(4-hydroxyphenyl)propanoic acid)」;Synthesized by hydroxylation of phenylalanine.When the aromatics are further hydroxylated, L-dopa(C9H11NO4:L-3,4-dihydroxyphenylalanine:(S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid.It is converted to L-Dopa by tyrosine hydroxidase and to dopamine(Nerve cells in a specific area of brain, which is the final product.)by decarboxylase.The neurotransmitter catecholamines (noradrenaline:norepinephrine(C8H11NO3),adrenaline(C9H13NO3):Mainly adrenal medulla(副腎髄質)cells can be metabolized, etc.) are produced from L-Dopa.)is produced.When oxidized by tyrosinase, the intermediate L-Dopa is immediately oxidized and converted to dopachrome(C9H7NO4).It is further polymerized by the action of enzymes and converted to melanin.It is a dark brown pigment and is widely distributed in animal tissues such as skin, hair and iris.I hear that it has a role to absorb excess sunlight.A disease in which tyrosinase is congenitally deficient is known as oculocutaneous disease (albino:Mutant individuals who cannot synthesize photosynthetic pigments:先天性白皮症).etc.
トレオニン(スレオニン:C4H9NO3:2-Amino-3-hydroxybutanoic acid):A zwitterionic compound having an Amino group (-NH2) and a carboxyl group (-COOH) and a hydroxyethyl group in the side chain.There are two diastereomers, but only the (2S, 3R) form is called L-threonine(Since it has two optically active centers, four isomers have been identified.).It has been suggested that it may compete with alanine, Branched Chain Amino Acids, phenylalanine, serine, tryptophan, tyrosine etc.I hear that it is the newest in history.
トリプトファン(C11H12N2O2:2-Amino-3-(1H-indol-3-yl)propanoic acid):A raw material for Nicotinic acid:C6H5NO2 (Niacin:Vitamin B3) in the human body and Serotonin(It is deeply related to important human functions such as mental (stress) and sleep;Endorphin), a neurotransmitter involved in sedation and sleep-inducing action in the brain.Operate the sodium and potassium pumps to discharge the sodium incorporated into the conjugate with glutamic acid.When glutamate and lactic acid are taken up by nerve cells, the most important nerve, the glutamate nerve, begins to move.Glial cells(Oligodendrocytes(希突起膠細胞)that make myelin sheaths(髄鞘)to increase nerve conduction velocity, microglia(小膠細胞)that are responsible for central nervous system immunity, etc.Featured “astrocytes”(Glial fibrillary acidic protein Immunohistochemistry):kallikrein-related peptidase 7:(KLK7):Serine Protease(Proteolytic enzyme with serine group):To elucidate the generation mechanism of neuroglioma.)take up glucose and activate glutamatergic nerves.
バリン(C5H11NO2,SMILES:CC(C)[C@@H](C(=O)O)N):Energy is metabolized in muscle tissue and is involved in growth.Branched Chain Amino Acids(BCAA:Similar to leucine and isoleucine):Expected to adjust the nitrogen balance in blood and improve liver function.
ヒスチジン(C6H9N3O2:2-Amino-3-(1H-imidazol-4-yl)propanoic acid:It is said to have the effect of suppressing oxidative stress (ischaemia reperfusion), and there are cases of action such as increased insulin secretion.When neonatal screening is abnormal and when amino acid acid metabolism disorder is presumed:I heard that an increase in a specific concentration is a powerful clue to the diagnosis.In the nutritional disorder called cardiac cachexia seen in Chronic congestive heart failure, etc., aromatic amino acids increase and branched chain amino acids and histidine decrease.Since it is abundant in “hemoglobin(Proteins present in red blood cells)”, there is a risk of anemia if it is insufficient.In some cases, it was suggested that the anti-obesity effect was attenuated by “proline(Pyrrolidine-2-carboxylic acid)”.
アルギニン(C6H14N4O2:(S)-2-Amino-5-guanidinopentanoic acid);Expected to help the body produce energy, increase growth hormone secretion, build muscle, and improve male function.Promotes fat metabolism to strengthen muscle tissue and promote height growth.TCA cycle:Adenosine Triphosphate(C10H16N5O13P3),It enhances the function of the urea cycle in the liver and promotes the recovery of brain fatigue quickly.Ammonia(NH3)inhibits its function, but ingestion promotes detoxification.Expected to be effective as part of the Natural Moisturizing Factor(NMF)of the stratum corneum.
アラニン(C3H7NO2:2-Aminopropanoic acid);It is a synthetic raw material for sugar and has the energy generation function of the living body.The action of secreting the hormone Glucagon(Peptide hormone:29 amino acid;In the Liver, it activates protein kinase a through binding to specific receptors and cyclic adenosine monophosphate (AMP:cAMP-dependent protein kinase (Protein kinase A);Protein kinase(Phosphorylating enzyme)) production., which is secreted when blood sugar concentration is low and promotes the breakdown of glycogen(C6H10O5)n:Discovered as a liver component by Mr. Claude Bernard in Burgundy, France in 1856.
アスパラギン酸(C4H7NO4:Aminosuccinic acid, asparagic acid;The role of increasing the absorption of K and Mg and decomposing and promoting lactic acid.Located closest to the TCA cycle of the body, which is the place of energy production.)It is located closest to the TCA cycle(Tricarboxylic Acid Cycle:Citric Acid Cycle)of the body, which is the place of energy production.In 1937, German's chemist and doctor Hans Adolf Krebs finds the circuit.England:Received the Nobel Prize in Physiology or Medicine in 1953.Discovery of the Ornithine cycle of Urea synthesis:A cycle that draws out internal combustion.Decomposes fat and lactic acid and converts them into energy(Tricarboxylic Acid Cycle).
グルタミン酸(C5H9NO4:2-Aminopentanedioic acid:In animals, it can be synthesized from non-essential amino acids, that is, other organic compounds.Discovered by Mr.Karl Heinrich Leopold Ritthausen in 1866 in the acid hydrolyzate of gluten, a wheat protein.It is famous as a raw material for glutathione and GABA (4-aminobutanoic acid).It can be biosynthesized from "2-Oxopentanedioic acid" and "ammonia(NH3)".It conveys information to nerves by binding to and activating N-methyl-D-aspartic acid (NMDA) -type receptors.D-serine(It has the enzyme serine racemase (SRR) synthesized by Glial cells(It acts to give an energy source to nerve cells in the brain and builds an energy environment:A cell that fills parts of the brain other than nerve cells and supports the functions of nerve cells from various aspects.)located in a specific region of the hippocampus.)regulates stimulus volume.It is believed that the Synapse connection will be strengthened, giving memory and learning.There seems to be a hypothesis that the diseases alzheimer dementia and amyotrophic lateral sclerosis are caused by too much stimulation of the “NMDA receptor”.)
グリシン(Glycocholic:C2H5NO2:Aminoethanoic acid);In the Nerve system, it also functions as an amino acid (Collagen:Protein,Elastin(Elastic fiber),Keratin(△Cystine), Sericin(C30H40N10O16).), which is mainly responsible for inhibitory synaptic transmission between the brain stem and spinal cord.The feature is that there are no stereoisomers(The opposite sex with different three-dimensional directions of atoms in space.)such as D-form and L-form.Not only does it improve the shelf life of food, but it also has a sweet taste and is used as a seasoning.Porphyrins(Porphyra;Hemoglobin as an oxygen carrier in human blood (Erythrocyte) is prominent.) related to the function of carrying oxygen in the blood and creatine(C4H9N3O2;A small amount in the brain.)essential for muscle exercise.
プロリン(C5H9NO2,SMILES:OC(=O)C1CCCN1):The main composition of collagen(Protein;A polymer compound formed by linking (polymerizing) a large number of 21 types of amino acids in a chain:Hydroxyproline(C5H9NO3)), which is abundant in gelatin and animal skins.When stored, aspartic acid tends to decrease and increase.It is high in fruit amino acids.
セリン(C3H7NO3:2-Amino-3-hydroxypropionic acid);A raw material for Phosphatidylserine(C13H24NO10P,Phospholipid- Signal transduction), a component of cell membranes.It is one of the important moisturizing ingredients to maintain the moisture content of the skin, and can be a raw material for “glycine” that is close to the same ingredient.It is the Natural Moisturizing Factor (NMF:Small molecules such as Amino acids, pyrrolidone carboxylic acids (and their salts), urea, mineral salts, organic acids (and their salts).) of the skin and is the most abundant in amino acid.
エリオシトリン:C27H32O15
ネオエリオシトリン:Eriodictyol(C15H12O6);It is metabolized and absorbed by eriodictyol and found in blood and urine as a glucuronide conjugate.Similarly(homoeriodictyol(C16H14O6),hesperetin(C16H14O6)), the role of inhibitory activity of lipoxygenase (5-LOX and 12-LOX).
ノミリン:TGR5:Transmembrane G protein-coupled Receptor 5:G protein-coupled receptor:C28H34O9 (mw514.57).Bile acids exert anti-obesity and anti-hyperglycemic effects through a G protein- coupled receptor TGR5:Ligand active food ingredient.By binding, it promotes insulin secretion from L-sell. It promotes the secretion of hormone GLP-1.In the living body, it binds to TGR5(G protein-coupled bile acid receptor)of skeletal muscle to increase heat production and exerts an anti-obesity effect through increased energy consumption.The non-sugar moiety that remains after the glycosyl group of the glycoside is replaced by a hydrogen atom:Aglycone;Phytochemical
リモネン:monoterpene:1-Methyl-4-(1-methylethenyl)-cyclohexene:C10H16;A terpenoid compound having two double bonds in which two isoprene units (C5 units) are linearly bonded to form a single ring (six-membered ring).
アクリドン:acridinone,1948:C13H9NO
ポリメトキシフラボノイド類(PMF):ノビレチン(C21H22O8);Long-term potentiation in the hippocampus (LTP):In cognitive impairment such as Alzheimer's disease, synaptic plasticity disorder occurs due to various factors.cAMP response element-binding protein(cAMP-responsive element),I hear that it is cre-dependent transcriptional activity that follows.Expected to have Aβ deposition inhibitory effect and nerve growth factor (NGF) -like effect.
タンゲレチン(C20H20O7)
シネンセチン(C20H20O7);InChI=1S/C20H20O7/c1-22-13-7-6-11(8-15(13)23-2)14-9-12(21)18-16(27-14)10-17(24-3)19(25-4)20(18)26-5/h6-10H,1-5H3,SMILES:COc1ccc(cc1OC)c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1,及び,3,5,6,7,8,3′,4′-ヘプタメトキシフラボン(HMF):Induces the production of brain-derived neurotrophic factor (BDNF; 脳由来神経栄養因子).
γ(gamma)-aminobutyric acid:C4H9NO2;It is responsible for inhibitory synaptic transmission of the rostral central nervous system(Free amino acid series).Glutamic acid by decarboxylation catalyzed by glutamic acid decarboxylase (enzyme:GAD67(GAD1:cytoplasm),GAD65(GAD2:presynaptic terminal)).TCA cycle α-ketoglutaric acid(C5H6O5)to glutamic acid.In some cases, blood pressure lowering effect is achieved by suppressing the release of norepinephrine from pars sympathica:Ion channel type receptor.etc.
ポンシリン:(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4, 5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one;C28H34O14:Flavonoid glycoside with the structure of isosakuranetin(C16H14O5)7-O-neoheseridoside.It acts to inhibit osteoclast differentiation and bone loss through down-regulation of NFATc1(Nuclear factor of activated T-cells, cytoplasmic 1:OSCAR,TREM-2,PIR-A etc.)in vitro and in vivo.
ネオポンシリン(ジジミン):(S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one;C28H34O14:Suppression of NF-κB(Protein complex;Nuclear factor-kappa B)activation:Prevent vegf Induced angiogenesis in vitro and in vivo.
カリウム:K;It interacts with “sodium”, which is abundant in extracellular fluid.It works to maintain the osmotic pressure of cells and retain water.After ingestion and absorption in the small intestine, it is transported to tissues throughout the body, most of which is excreted by the kidneys.It is maintained by regulation of reabsorption in the kidney, and the k concentration in blood is maintained between 3.6 and 4.8 meq / l.Together with sodium, it maintains cell osmotic pressure.It works to suppress nerve stimulus transmission, functional regulation of heart and muscle, and intracellular enzyme reaction(I have to add proton transfer equilibrium).I heard that about 200g is contained in the body of an adult:Potassium.
カルシウム:Ca;In the body, the amount in cells and blood is strictly controlled.Tendency to move from bone to blood as needed.About 99% is stored in bone, but also in the blood of cells and muscles.If you don't get the calcium you need, you risk mobilizing large amounts of calcium in your bones and weakening your bones.To maintain normal blood calcium levels, it is necessary to take at least 1000-1500 mg daily.Parathyroid hormone(PTH)and Thyrocalcitonin(Made by the cells of the thyroid gland, hormones have the function of lowering the calcium concentration in the blood by delaying the breakdown of bones.);It is made up of four parathyroid glands behind the thyroid gland in the neck.As the calcium concentration in In blood rises, the amount of hormones produced by the parathyroid glands tends to decrease.It stimulates bones to release calcium into the blood and reduces the amount of calcium excreted by the kidneys into the urine.Increases calcium absorption by stimulating alimentary canal to increase calcium absorption by promoting the activation of vitamin D in the kidneys.
マグネシウム:Mg;Vinegar has been known to solubilize insoluble calcium (Ca) and magnesium (Mg) in food, however, the difference in solubilization ability among various kinds of vinegar has not been investigated. In this study, solubilization of Ca and Mg from coral powder and beef bone powder was compared with several kinds of vinegar. Calcium solubilization was observed to be high in grain vinegar, cider vinegar and wine vinegar, and low in rice vinegar and un-polished rice vinegar. On the other hand, magnesium solubilization was high in rice vinegar, wine vinegar and cider vinegar, and low in grain vinegar and un-polished rice vinegar. Calcium solubilization of coral powder was significantly negatively correlated with the pH of vinegar, while Mg solubilization was not. Comparison of solubilization of Ca in un-polished rice vinegar and acetic acid solution suggested that the phosphorus content was also responsible for solubilization in un-polished vinegar. These results suggest that ingredients in vinegar, as well as acidity and pH, affect solubilization of Ca and Mg from food when cooked with vinegar.Characterization of Solubilization of Insoluble Calcium and Magnesium with Various Kinds of Vinegar,Nakano Central Research Institute, Nakano Vinegar Co., Ltd. and Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University with Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology 45(11), 655-662, 1998-11-15)
ナトリウム:Na;In the adult body, most of it is contained in extracellular fluid outside the cell.Approximately 50 % as salt (sodium chloride), bicarbonate, phosphate.About 40 % is present in the build and is slightly contained in the intracellular fluid.Functions such as osmotic pressure adjustment:Roles such as maintaining the amount of extracellular fluid.Normally, healthy people do not have a deficiency.It is possible to promote the excretion of sodium by taking vegetables and fruits that are high in potassium together.This is because it has been confirmed that taking too much increases the risk of swelling, thirst, high blood pressure, stomach cancer, and esophageal cancer.
リン:P;(Leakage in urine causes symptoms such as hypoproteinemia, decreased renal function, and hyperphosphatemia.)The amount of phosphorus per 1 g of protein contains about 15 mg, and the intake correlates with the protein intake.The role of combining and strengthening bones and teeth.Higher blood phosphate levels tend to make bones brittle.Calcium tends to combine and become coal in other than bones such as blood vessels and tendons.
鉄:Fe;It is attracting attention as one of the world's three major deficient micronutrients along with vitamin A and Iodine(I2;.In 1811,Discovered by burning seaweed with potassium carbonate, which is the raw material for potassium nitrate by Bernard Courtois(仏).)Non‐heme iron(Fe)(Included in vegetables, eggs and milk.);By taking it with foods rich in high-quality protein and vitamin C, the absorption rate into the body is improved.Fe shortage of women due to blood loss, a big problem for expectant mother and lactating women whose demand increases.Due to the metabolism of the body, about 1 mg of iron(Fe)is lost in adult men and about 0.8 mg in women per day.Ferritin(A globular protein complex consisting of 24 proteins.)has a role of suppressing deficiency and excess, and is also called stored Fe.About 90% of anemia is iron deficiency, which is deficient in fe, one of the important materials of hemoglobin.
銅:Cu;It has been known for a long time as a trace essential mineral, which is present in the human body at about 80 mg.It binds to proteins and plays a role in catalyzing a wide range of in vivo reactions.Tendency to be mainly present in bone, skeletal muscle and blood.Although it is involved in hematopoietic function as well as Fe, no reports have been heard regarding the adverse effects of chronic overdose, except for some diseases.Monovalent compounds exist as insoluble salts and complex salts.Divalent salts and complex salts are common.It is absorbed from the small and duodenum and transported to the liver through the portal vein.I hear that the lower the intake, the higher the absorption rate, and the higher the intake, the lower the absorption rate.Large amounts of divalent iron and tin ions competitively inhibit the absorption of copper from the gastrointestinal tract.Inborn errors of copper metabolism(Wilson’s disease):Protein binding:Hepatolenticular degeneration.It acts as a Cu enzyme and acts as a catalyst for various reactions such as O2 transport, electron transfer, redox, and O2 addition.Important for Fe metabolism and transport, removal of active oxygen, and metabolism of neurotransmitters.Deficiencies can result from hereditary malabsorption or are acquired, but are not found in the normal life of healthy people.On the other hand, cases of symptoms are given to Babies whose main source of nutrition is low-content milk.Insufficiency may cause anemia, leukopenia, and bone abnormalities that do not respond to Fe administration.In addition, there are decreased immune function, cardiovascular abnormalities, and abnormal cholesterol and glucose metabolism.However, this is less frequent.
亜鉛:Zn;Zinc‐deficiency symptom:A state in which the zinc concentration in the blood is below 80 μg / dL to 130 μg / dL.Dermatitis, stomatitis, alopecia, pressure ulcer due to lack.Loss of appetite, developmental disorders, hypogonadism, susceptibility, dysgeusia, anemia, infertility, etc.Various symptoms occur and tend to improve with zinc supplementation.
マンガン:Mn;Functions as an enzyme activation and a component of metal enzymes.It is a silver-white metal with an atomic number of 25 and an atomic weight of 54.94, and its surface is oxidized in the air.I hear that 12(For a weight of 70 kg)to 20 milligramme is present in the body of an adult.It acts directly with many elements, gradually reacts with water, and is easily dissolved in acids.Absorbed by inhalation, oral or transdermal:Ingested from the diet, it dissolves as divalent by gastric acid and becomes trivalent by the oxidative mechanism of intestinal cells.It is absorbed, transported to the liver through vena portalis, secreted from the bile into the intestinal tract, and mostly excreted as feces.Since absorption competes with Fe, manganese tends to be less likely to be absorbed if the iron content in the diet is high.It is abundant in mitochondria, and is contained in high concentrations in pigmented areas in the body such as the retina, hair, and skin pigmented areas.It suggests specific and non-specific effects on many enzyme activities such as oxidoreductase, hydrolase, dehydrogenase, and transferase.It is also a component of arginine-degrading enzyme, lactate dehydrogenase, and manganese superoxide dismutase (MnSOD).Examples include connective tissue and bone formation, inner ear growth formation, glucose tolerance, fertility, lipid metabolism, growth and involvement in brain function.
【効果効能】
抗癌作用:Anti-cancer effect
抗酸化作用:Antioxidant effect
抗菌作用:Antibacterial effect
抗腫瘍性:Anticancerous
肩こり:Stiff shoulder
腰痛:Lumbago
髪の毛健康:Hair health
風邪予防:Prevention of cold
美肌・美容:Beautiful skin and beauty
老化防止:Prevention from getting older
ダイエット:Diet
むくみ解消:Edema
利尿効果:Diuretic effect
女性ホルモン:Female hormones
妊婦:Expectant mother
貧血:Anemia
疲労回復:Recovery from fatigue
視力維持:Maintaining eyesight
消化促進:Digestion promotion
殺菌効果:Bactericidal effect
骨粗しょう症:Osteoporosis
新陳代謝:Metabolism
ストレス解消:Stress relief
活性酸素抑制:Reactive oxygen species suppression
喉・呼吸器安定:Throat, respiratory stability
皮膚粘膜強化:Skin and mucous membrane strengthening
高血圧:Elevated blood pressure
肥満:Corpulence
生活習慣病:Life style related disease
血中コレステロール緩和:Blood cholesterol relief
コレステロール:Triglycerides
二日酔い:Overnight drunkenness
心筋梗塞:Heart infarction
脳梗塞:Brain infarction
血栓予防:Thromboprophylaxis
食欲不振:Anorexia
精神安定:Tranquilize
認知機能改善:Cognitive function improvement
胃潰瘍:Gastric ulcer
胃腸障害:Gastrointestinal injury
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