C. melo(鶴岡市,酒田市)When it grows, the signs of fiscal consolidation accelerate surprisingly, and when it declines, it becomes unhealthy. Don't waste the wisdom and effort of our predecessors. Promote response to epidemics and review supplementary budgets-黒字化



【製品名(商品名)】
庄内メロン(Shonai sand dunes specialty), ルピアレッド
【種類】
Cucumis melo L. 
【生産地】
山形県鶴岡市, 酒田市
【名前の由来】
The details are still in the learning stage, but it can be imagined from the red meat Melon species. Primary balance has been whispered in recent years, and the “G20; Its predecessor is the political system between governments consisting of France, the United States, the United Kingdom, Germany, Japan, Italy, and Canada ≒ G7, 1975” is the only country in Japan that has adopted fiscal discipline. Encourage debt-to-GDP ratio ≒ Government Debt, to profitability.  (It's good if the ratio goes up, it's important to maintain it.) It's natural to learn the correct way of thinking, but I would like to talk a little about the economy. Indonesian currency unit. The currency code is “IDR” and the sub-currency is “Sen”; Auxiliary currency unit of Southeast Asian countries”, and 1 rupiah= 100 cents. The name “Rupiah comes from the Indian currency “Rupee”. Since the latter half of 1997, the economic crisis has occurred due to a shortage of foreign currency, and the exchange rate has fallen to one-sixth in half a year. Floating exchange rate system: Consideration of Treasury and Asian central bank Denominations: Devaluation of currencies, all domestic assets and liabilities. If the number of digits displayed in the currency amount becomes large due to inflation etc., it may hinder economic activities. If the country grows, it is natural that debt will increase, and it can be predicted that the ratio to GDP will increase. It is certain that the ratio will increase from debt.
【主な特徴】
The Shonai Dune is the longest dune in Japan, with a length of 34 km, a width of 1.5 to 3km, and a maximum altitude of 77m from Yuza Town, Akumi District to Tsuruoka City via Sakata City, but its existence is unexpectedly unknown. Geologically speaking, it is said to have a two-layer structure of old dunes and new dunes. It is said that the entire dune was covered with broad-leaved trees during the period between the formation of old dunes and new dunes, which is the Jomon period. Since the winter monsoon has been a source of trouble for many years because its unimaginable strength has been an obstacle to the Shonai Plain, the ancestors squeezed their wisdom to protect the fields of rice and vegetables, and the harm of sand. , Has a history of protecting the plains from wind damage. In the 1700s, the Shonai Domain began to provide guidance on tree planting by deciding to be a tree planting supervisor (planting role). In reality, the owners of each region invested their own money to plant trees. In each area of ​​the long dunes, we have fought against flying sand. Even before Mitsuoka Honma-Ko planted trees, there were thickets in the dunes. It is often said that he has achieved his achievements, but it is known that Kimoiri (Sponsorship / a local lord) and others took the initiative in planting trees in both Yuza and Shonai. A famous person is Taroemon Sato-Ko(His grandfather Jiroemon-Ko moved to Barashinden (Currently Tsuruoka City) and his father Zengoro moved to Hirooka Shinden Village (currently Sakata City), contributing to water control and agricultural promotion in the lower Akagawa River for generations. Taroemon-Ko became a planter of Kyoden Dori in 1745, and was involved in the development and planting of new fields such as Sakanobe Shinden Village (currently Sakata City).)-Ko, who is now in Sakata City. However, since it is used as fuel for salt production, it was cut down more and more, and the flying sand became worse again. So Mitsuoka(A wealthy merchant in Dewa Sakata. His real name is Shiro Saburo. In 1775, he was ordered by Tadaari SAKAI-Ko, the 7th lord of the Shonai domain and founder of the domain school, and was involved in the financial reform of the exhausted domain and achieved reconstruction.)-Ko tried to build a windbreak again. Prevention of flying sand was a pressing issue for local residents. So they should have responded voluntarily without being asked. Under such circumstances, only those who threw their own fortune and planted trees have left their names in posterity. Even those who make a living by fishing are in an environment where they cannot live without making their own rice, which was a serious problem for those who are doing paddy fields in the neighborhood. I think we must not forget that the current Shonai Plain is being protected by the steady efforts of our great ancestors. A wealthy farmer and a great merchant capitalist in the late Edo period. Mitsuoka -Ko: 1732-1801, the third owner of the Honma family, with permission from the clan from the 8th year of the 1758, donated 600 private property and planted sabo forests on the west beach of Minato Sakata. Many a little makes a mickle: Stack small to make big. He is the number one landowner in Japan and created a sabo forest under the philosophy of “The gain is special, the loss is also gained”. As the “first wealthy farmer in the world,” he was the landowner of 240,000 koku(1石 is 150 kg of rice)in the territory of the Shonai domain. Gold and silver goods are piled up like a mountain, and in the warehouse of 伊呂波 48 warehouse, you should be able to count a lot of rice bales, gold and silver, bronze coins, banknotes, old coins, etc. It is said to be the ancestor of the Honma family Resurgence in Ugo Sakata, which was rumored to be. Akakawa River runs from the south to the north of Tsuruoka to Sakata. Originally it merged with the Mogami River, but since it was flooded a lot and caused damage, a floodway was created through the dunes. At that time, the remains of the Jomon period appeared, so it was verified and many facts and speculations were made. There is an impermeable layer of dark soil on the old sand dune of Shonai sand dune, and since the water of the aquifer there was available, there is now melon cultivation, and there is future investment. It was realized with the efforts of various people, such as breeding suitable for taste and cultivation, but since the aquifer was discovered after the war, it is now possible to pump up groundwater and irrigate it. It is clear that upland farming has become possible. People have lived in the Shonai sand dunes since the Jomon period, but the Jomon archaeological site in Shonai stuck to the periphery of the plain. In the Heian period, village traces began to be seen on the flat ground for the first time, and it seems that the flat ground was a wetland and almost no people could live in it. Melon was introduced into the Shonai sand dunes around 1918, and has a history as old as other production areas such as Hokkaido. It is presumed that the prototype was made by some enthusiastic farmers when it was first introduced. After that, cultivation spread in the sand dunes under the guidance of the “Nanakubo Melon Study Group” formed around the “Nanakubo Shionen(Current Orphanage; 鶴岡市下川窪畑)” established by Mr. Yoshihiro Igarashi in September 1931. It is said that the study group cultivated many varieties, selected varieties suitable for the area, and secured seeds. It is said that the period from 1935 to 1936 was the peak of cultivation before the war, with more than 250 cultivated farmers and a cultivated area of ​​22 ha or more. Agricultural experimental station sand dune test site was established in 1936 amid the growing heat of melon cultivation, and suitable varieties were selected and varieties were cultivated. Cultivation was suspended during the war due to increased food production, but after the war, demand for high-quality fruits increased due to changes in lifestyle, and melon cultivation was revitalized. Mr. Saburota HINO (Principal of Nanakubo Shionen) made efforts to collect foreign seeds in order to introduce more delicious varieties. However, he heard that new varieties were being developed because it was difficult to find one that matched the tastes of consumers. Since 1953, Mr. Yoshio Higuchi (Nanakubo Shionen), Mr. Matsutaro Saito (former Nanakubo, Nishigo Village, Nishitagawa District), Mr. Michio Umeki (former Nanakubo, Nishigo Village, Nishitagawa District) and others have been mating melons, and since 1954, the Agricultural Experiment Station The sand dune branch has begun full-scale variety development. The varieties developed by individual breeders and public test sites include “Akebono, Shirotae, Shion, Life, Silk, Daily, Dewa Gold, Sun Gold”, and “Sun Jewel”. Since the 1965s, commercial varieties developed by seed companies have been cultivated. There are “Prince melons” that have increased since 1967, “Andes” that have been cultivated in earnest since 1978, and red meat melons that have increased since Heisei. In particular, “Andes” has gained popularity as a variety for general households due to its excellent appearance and taste due to its net, and Kumamoto, Ibaraki, and Shonai have become known throughout the country as the three major production areas. Tsuruoka's original brand, “Tsuruhime” with blue meat and “Tsuruhime Red” with red meat, which debuted in the market in 1998, have also become popular. In addition, the sweet and juicy “Summer Quincy” of red meat seems to be highly evaluated. With a stable production system that includes the greenhouse Earl's melon, Yamagata Prefecture's melon production is the fourth largest in Japan, and it is no exaggeration to say that Yamagata Prefecture supports the summer melon market. Forcing cultivation and controlled cultivation are also carried out by the house of the open-field net melon, and there is also the house cultivation of high-grade Earl's melon. In particular, the original Earl's variety “Yamagata Melty” is attracting attention for its good quality and is highly expected, according to market participants. In this way, the prefecture ships both open-field net melons and high-end melons under a stable production system while also using the house. Heading to the melon producing area of ​​the Shonai sand dunes, you will see several large sake breweries on the way. It is the Oyama Area of Tsuruoka city where the breweries are lined up. I heard that there is good quality groundwater in this area, which is the source of famous rice wine. A well-drained dune is good for melons. If there is a lot of water, the melons will absorb it and the sugar content will not rise. And the strong sunlight during the day, the coolness at night, and the best groundwater. Matched, said the producer. The mesh (net) on the surface of the melon refers to the union of cracks in the fruit, which is formed by the sudden growth of the fruit. If you get fat round and clean, the net will be fine and even. This is how to identify a good melon.  From the story. The main purpose of preventing sand flying is to protect paddy fields. Instead of planting pine trees to take advantage of the dunes, we had to plant pine trees to prevent the flying sand from damaging the paddy fields on the flat ground. Residents of the flat ground also participated in the tree planting work, and such a difficult time continued for a long time. And to some extent, when the pine trees were planted and the flying sand was settled, I decided to use this land for the first time, but at that time I did not know the existence of water and there was no pump, so I could get water. He said he had a lot of trouble. Since we were farming with water on our backs and irrigating, we were barely able to eat what we were eating. I can see the unimaginable determination and spirit. It wasn't so long ago that I had such a hard time. Until just after the war, such a situation continued. When I think of sand dunes, I think of Tottori and Hamamatsu, and I get the impression that the sand moves, but the sand does not move in the Shonai dunes. It is a well-known fact that even people who have no connection with the area can understand, and people have made great efforts to keep it from moving. In addition to planting Japanese black pine, we also planted jetties to control coastal currents, fences to protect the planted seedlings, and highly resistant grasses such as Japanese rose and Japanese silver berry on the coastal shoreline side. After guarding the sand with them, black pine was planted in the rear. It wasn't completed because the tree planting was finished, and the windbreak couldn't be maintained unless it was continuously renewed. Currently, the biggest challenge is the damage caused by Bursaphelenchus xylophilus. The coastline of Akita is almost wiped out. For that reason, they are controlling pests. The pine trees planted in the narrow road between the fields are under individual control, and if they grow too large, they will be shaded, and if they fall, the agricultural house will be destroyed. And replant. Without this, the agricultural house would collapse. It seems that strong winds were a concern even when Shonai Airport was opened in such a windy area. Especially in winter, the northwest wind is strong, and the windbreak is about 300 m wide, so I heard that this strong wind cannot be prevented without that width. For generations, while squeezing the sand around the resident's house, it looks like a house is being built in the dunes. Carry the sand on your back and go to the beach to throw it away. It seems that if the northwest wind blows in winter, the house will really be filled. If too much sand accumulates, you can't farm very much. Hamanaka, Tsuruoka is a village of people who were fishing for seine nets. Therefore, even if the damage caused by flying sand is great, it was decided to form a village as close to the sea as possible. Mikado Kyowa : Under the Lima Gran Group, Kyowa Seedling Co., Ltd. and Mikado Breeding Farm Co., Ltd. merged in 2007 and started as “Mikado Kyowa Co., Ltd.” Hokkaido Branch: Kita 3-jo, Chuo Word, Sapporo City, Hokkaido: Onodai, Midori Word, Chiba City, Chiba. Rupiah Red was announced in 1990 from the mating of (IK × Andes) × Earls, and is known as a popular red meat net melon that is easy to make. It is a middle leaf with medium internodes and a little strong grass. Female flower settling and fruit set are stable and good. The fruit is a regular sphere inside and outside 1500 g, the skin color is grayish green, the net is dense and evenly expressed, and it rises a little. The flesh is dark orange and thick, and the lenticel green flesh is slightly thin. It is hard to become hollow fruit and seeds do not flow. The sugar content is high and stable at 16 degrees inside and outside, the meat quality is rich in melting quality, and the taste is good. 53 days after flowering, it matures properly inside and outside, and 3 to 7 days after harvest is the best time to eat, which is a delicious time. It is hard to vine, has good female flower settling and fruit set, and is easy to cultivate. In addition, it is resistant to Fusarium oxysporum; つる割病 (race 0,2) and is resistant to powdery mildew. The optimum temperature for germination is around 27 ° C, and after germination, the seedlings are transplanted to a seedling raising pot and gradually acclimatized to low temperatures. The standard amount of fertilizer applied is nitrogen 8-10kg / 10a, phosphoric acid 15-20kg / 10a, K 10-12kg / 10a. It is advisable to add enough good quality compost so that the fertilizer effect will last for a long time. Beds should be prepared early, mulched and tunneled, and warm enough. Plant after the soil temperature can be secured at 16 ℃ or higher. No special cultivation technique such as “steaming” is required. Throughout the growing season, the maximum temperature is 28 ° C, the eve temperature (temperature until 12:00 pm) is 12 ° C, and the minimum temperature is 10 ° C. From around the mating period until the net is completed, I would like to aim for a temperature of 15 ° C the night before. When the outside air is cold, pay attention to the ventilation volume and wind direction so that the outside air does not come into direct contact with the crops, and devise ways such as making the film in the tunnel inside the house half-open to make it a tsuitate. Irrigation should be done around the time when the resulting branches are aligned, after confirming fruit set and during the horizontal net development period, and irrigation should be modest from about 10 days before the harvest time. The number of days from flowering to harvest is about 55 days, depending on the cultivation season and grass vigor, and it seems that harvesting may take 60 days in the low temperature period and 50 days in the high temperature period. Discoloration of the fruit stem, change in skin color, result: Soil deficiency of the first leaf of the branch, cracks in the fallen cork, thin nets between the nets, etc. It is good to judge and judge the harvest. A popular red meat melon that is easy to make, has a high sugar content, and has a nostalgic scent. The flesh is soft, the mouthfeel is mellow and juicy. Although the net (stitch pattern on the skin surface), which is a marker of sweetness, has a high density, it is famous as a variety whose sweetness tends to decrease because it is vulnerable to a hot and humid environment. Shonai Hiyori: “Hiyoriyama Park”, where the setting sun over the Sea of ​​Japan stimulates travel, is also a famous place for cherry blossoms, and the Sakata Hiyoriyama Cherry Blossom Festival is held every April. Inside the park, there are Japan's oldest wooden hexagonal lighthouse, directional stones, and a Sengoku ship that was active in the past, creating the atmosphere of a port town.
【栄養素・機能性成分】
Protein: macromolecule; Structural proteins make up the body, and functional proteins are proteins involved in digestion, transportation, and chemical reactions. Digestive enzymes such as pepsin(aspartic endopeptidase)and trypsin(Endopeptidase & Serine Protease), which are cut by digestive enzymes and decomposed into small peptides and amino acids, absorbed and digested finely, are also made from amino acids.
脂質 ; It has important roles such as being used as an energy source, becoming a component of cell membranes, organs, and nerves, and assisting the transport of vitamins. It keeps a person's body temperature, moisturizes and glitters the skin, helps normal hormones work, and has an active function. Women, in particular, can be detrimental to beauty and health and need some lipids for beautiful skin and hair.  However, if the intake is too high, it will be stored as fat.
炭水化物; It is a compound of carbon(Ca)and hydrogen(H), and is divided into sugar, which is taken into the body as food and used as an energy source, and dietary fiber, which cannot be digested by digestive enzymes in the body.
βカロテン: C40H56; Converted to vitamin A in the body as needed. Carotenoids that are abundant in green and yellow vegetables. It is important for maintaining the health of skin and mucous membranes and for photostimulatory response, and promotes cell proliferation. Approximately 25 times that of green flesh (melon, etc.) and general statistics.
ビタミンB1; Decarbonization in the ketoglutarate dehydrogenase reaction: Coenzyme; Form of thiamine pyrophosphate.
B2; The form of flavin adenine dinucleotide as a cofactor for the α-ketoglutarate dehydrogenase complex and succinate dehydrogenase.
B6; Pyridoxine(C8H11NO3), Pyridoxal(C8H9NO3), Pyridoxiamine(C8H12N2O2); Coenzyme for protein, lipid and carbohydrate metabolism: It acts as a coenzyme(Pyridoxal phosphate)for metabolism of bioactive amines, which is a neurotransmitter, and as a hormone regulator: Helps keep nerves and skin healthy, fight infections, keep blood sugar levels normal, produce red blood cells, and some enzymes work properly.
パントテン酸(Cofactor fused with active carboxylic acid residues such as Acyl coa and succinyl-coa: Coenzyme A(Cysteamine): C21H36P3N7O16S)
ナイアシン(The form of nicotinamide adenine dinucleotide as a coenzyme of isocitrate dehydrogenase, α-ketotoglutarate dehydrogenase, malate dehydrogenase.)
ビオチン(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid: C10H16N2O3S): ビタミンH; It is a colorless acicular crystal that is stable to neutral, acidic, alkaline, oxygen, and light, but weak to heat. It is released from proteins in food by biotinidase(dominant gene)secreted by the pancreas. It translocates into the blood and binds to biotinidase, a transport protein synthesized in the liver.
葉酸; ビタミンM(2S)-2-[(4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid: C19H19N7O6; Pteridine(C6H4N4)with para-aminobenzoic acid; PABA(C7H7NO2)and another or more glutamic acids. Most exist in the “Polyglutamic acid type” (A combination of multiple glutamic acids). I heard that it is absorbed from the epithelial cells of the small intestine after being converted to the “Monoglutamic acid type” (A form in which one glutamic acid is bound) by digestive enzymes in the digestive tract. It is soluble in acids and alkalis, but hardly soluble in pure water or ethanol, and tends to be insoluble in acetone(C3H6O), Diethyl ether((C2H5)2O), Chloroform(CHCl3), and Benzene(C6H6). In the polyglutamic acid type folate, sugar and protein are released and released in the cooking and processing of foods and in the gastric acid environment.It is decomposed into monoglutamic acid-type folic acid by an enzyme in the small intestinal mucosa and then absorbed into the cells of the small intestine. I heard that it is converted to 5-methyltetrahydrofolic acid by the enzyme(small intestinal epithelial cell). It is transported to the liver via the portal vein, and 50% of the whole body seems to accumulate. It is converted again and transferred to bile, which is reabsorbed from the digestive tract and supplied to tissues for transfer. It is required to return homocysteine, a risk factor for arteriosclerosis, to methionine etc.
ビタミンC: C6H8O6; Discovered as a Skorbut preventive factor by Royal Navy doctor James Lind in 1753. It removes rust from water-soluble parts of the body, such as blood and the crystalline lens of the eye, and also restores tired vitamin E. It is absorbed mainly from the small intestine as it is without being digested by the stomach. It is then carried in the blood, stored and dispersed throughout the body. It is characterized by its “antioxidant effect”, which inhales, captures a small amount of active oxygen obtained, and detoxifies it.Excessive growth damages DNA or Protein and reduces cell function.
ビタミンE: C29H50O2; It is divided into a total of eight compounds, four tocopherols(In nature, α, β, γ, δ.)and four tocotrienols. It is absorbed into the body from the intestinal tract via the lymphatic vessels together with lipids, and has a very strong antioxidant effect. Protects unsaturated fatty acids and other fat-soluble components that make up biological membranes from oxidative damage: Included in the phospholipid bilayer of cell membranes. It suppresses the production of lipid peroxide, keeps blood vessels healthy, and suppresses the oxidation of LDL(Bad cholesterol)cholesterol in the blood. You will not have hypervitaminosis with a normal diet, as you tend not to have cumulative actions in your body.
Xanthophyll; What is contained in chloroplast is a complementary color pigment of photosynthesis: Cycle; The conjugation becomes longer from violaxanthin to antheraxanthin and then to zeaxanthin.
ブドウ糖: C6H12O6: D-グルコース: Known as a component of cellulose, starch and glycogen. D-glucose(Dextrose, an organic compound.)and pure crystalline monosaccharides produced after the starch is completely hydrolyzed. It is divided into water-containing water containing molecular water of crystallization and anhydrous water containing nothing.
Sucrose(β-D-fructofuranosyl α-D-glucopyranoside); C12H22O11; 1-O-α-D-Glucopyranosyl-1-(hydroxymethyl)-β-D-arabinofuranose.
Fructose; C6H12O6:(ICSC: 1554): It is well known that it is a water-soluble white crystal and is the most soluble of all sugars in water.
Cucumisin: The first serine-type protease in plants. An enzyme derived from Charante (Muskmelon).
ペクチン: methyl ester: J. Braconnot, 1825(Rf): Galacturonic acid: carboxyl group: -C(=O)OH
セルロース:(C6H10O5)n; The main component of plant cell sell stones and plant fibers, and the most abundant carbohydrate on earth.
ヘミセルロース(Amyloid): Discovered by E. Schulze in 1891. The name of the polysaccharide extracted with alkali after extracting Pectin from cell wall carbohydrates. Xyloglucan(Angiospermae): With 1,4-β-D-glucan as the main chain, the α-D-xylose residue binds to the O-6 position of the D-glucose residue of 75%. It is distributed throughout the cell wall including the middle lobe, and I hear that it is hydrogen-bonded to cellulose. Tendency to exist as a storage polysaccharide in seeds.
アミノ酸: イソロイシン(C6H13NO2: 2-アミノ-3-メチルペンタン酸); Hydrophobic amino acid(BCCA). The role of promoting the uptake of blood glucose into skeletal muscle without an increase in blood sugar concentration. It works to suppress gluconeogenesis(A pathway that slowly reverses glycolysis from lactic acid, pyruvic acid, amino acid, propionic acid, etc. to produce D-glucose.)in the liver and to oxidatively utilize glucose. A zwitterionic compound having a leucine structural isomer and a sec-butyl group (-ch (ch3) ch2ch3) in the side chain.
ロイシン(C6H13NO2: 2-Amino-4-methylpentanoic acid); Activator of mTOR: mammallian Target Of Rapamycin(Atypical serine-threonine kinases present in two types of complexes: It senses nutrient sources such as glucose and amino acid, and plays a role of regulators in cell proliferation, metabolism, and survival.): There are insulin, IGF-1 (insulin-like growth factor 1: insulin-like growth factors 1), Testosterone, Nitric oxide, Muscle Contraction etc. An important factor that promotes protein synthesis(BCCA).
リシン(リジン: C6H14N2O2:2,6-diaminohexanoic acid)(含硫): It is known as a synthetic raw material for carnitine(C7H15NO3: Derivative)required for fat burning. In the human body, we also hear examples of promotion of glucose metabolism and its relationship with calcium absorption. L-Lysine Hydrochloride: Mol fileKCF fileDB search(HCl: hydrochloric acid)
メチオニン(C5H11NO2S: 2-amino-4-(methylthio)butanoic acid: AUG); It is a sulfur-containing amino acid containing sulfur and is converted into glutathione(C10H17N3O6S)and taurine(C2H7NO3S)in the body. It is also known as a biosynthetic raw material for carnitine involved in fat burning. Tendency to be metabolized in a series of reactions called carbon metabolism. Using methionine and ATP synthase as substrates, S-adenosylmethionine synthase catalyzes the biosynthesis of S-adenosylmethionine(C15H22N6O5S+): Protein methylation.
シスチン( C6H12N2O4S2: 2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid); The role of stabilizing the structure of Proteins. It is one of the sulfur-containing amino acids(The composition of Glutathione-SH(C10H17N3O6S), which is important for detoxification and antioxidant activity.)containing sulfur and has a unique aroma. It converts methionine to Cystathionine(C7H14N2O4S: A catalyst for β-synthase from Homocysteine(C4H9NO2S: 2-Amino-4-sulfanylbutanoic acid)and Serine.)in the human body. It is famous as a sulfur-containing amino acid in which two molecules of cysteine ​​are bound.
(芳香族)フェニルアラニン( C9H11NO2: 2-Amino-3-phenylpropanoic acid); In the brain, the role of Synthesizing Neurotransmitter Norepinephrine(C8H11NO3: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol; Monoamine(A chemical structure in which an amino group is connected to an aromatic ring by two carbon chains.))and Dopamine(C8H11NO2: Monoamine neurotransmitter). It is also known as a raw material for Tyrosine(C9H11NO3: 4-hydroxyphenylalanine; Protein production synthesis). Important for accelerating the amyloid assembly process. Adrenaline(Adrenal medulla): Epinephrine(C9H13NO3), Produced by neurons and released as adrenal medulla hormones and neurotransmitters.
チロシン(C9H11NO3: 2-Amino-3-(4-hydroxyphenyl)propanoic acid); Synthesized by hydroxylation of phenylalanine.When the aromatics are further hydroxylated, L-dopa(C9H11NO4: L-3,4-dihydroxyphenylalanine:(S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid. It is converted to L-Dopa by tyrosine hydroxidase and to dopamine(Nerve cells in a specific area of ​​brain, which is the final product.)by decarboxylase. The neurotransmitter catecholamines (noradrenaline: norepinephrine(C8H11NO3), adrenaline(C9H13NO3): Mainly adrenal medulla(副腎髄質)cells can be metabolized, etc.) are produced from L-Dopa.)is produced. When oxidized by tyrosinase, the intermediate L-Dopa is immediately oxidized and converted to dopachrome(C9H7NO4). It is further polymerized by the action of enzymes and converted to melanin. It is a dark brown pigment and is widely distributed in animal tissues such as skin, hair and iris.I hear that it has a role to absorb excess sunlight. A disease in which tyrosinase is congenitally deficient is known as oculocutaneous disease (albino: Mutant individuals who cannot synthesize photosynthetic pigments: 先天性白皮症) etc.
トレオニン(スレオニン: C4H9NO3: 2-Amino-3-hydroxybutanoic acid): A zwitterionic compound having an Amino group (-NH2) and a carboxyl group (-COOH) and a hydroxyethyl group in the side chain.There are two diastereomers, but only the (2S, 3R) form is called L-threonine(Since it has two optically active centers, four isomers have been identified.). It has been suggested that it may compete with alanine, Branched Chain Amino Acids, phenylalanine, serine, tryptophan, tyrosine etc. I hear that it is the newest in history.
バリン(C5H11NO2, SMILES: CC(C)[C@@H](C(=O)O)N); Energy is metabolized in muscle tissue and is involved in growth. Branched Chain Amino Acids(BCAA: Similar to leucine and isoleucine): Expected to adjust the nitrogen balance in blood and improve liver function.
ヒスチジン(C6H9N3O2: 2-Amino-3-(1H-imidazol-4-yl)propanoic acid); It is said to have the effect of suppressing oxidative stress (ischaemia reperfusion), and there are cases of action such as increased insulin secretion. When neonatal screening is abnormal and when amino acid acid metabolism disorder is presumed: I heard that an increase in a specific concentration is a powerful clue to the diagnosis. In the nutritional disorder called cardiac cachexia seen in Chronic congestive heart failure, etc., aromatic amino acids increase and branched chain amino acids and histidine decrease. Since it is abundant in “hemoglobin(Proteins present in red blood cells)”, there is a risk of anemia if it is insufficient. In some cases, it was suggested that the anti-obesity effect was attenuated by “proline(Pyrrolidine-2-carboxylic acid)”.
アルギニン(C6H14N4O2: (S)-2-Amino-5-guanidinopentanoic acid); Expected to help the body produce energy, increase growth hormone secretion, build muscle, and improve male function. Promotes fat metabolism to strengthen muscle tissue and promote height growth. TCA cycle: Adenosine Triphosphate(C10H16N5O13P3), It enhances the function of the urea cycle in the liver and promotes the recovery of brain fatigue quickly. Ammonia(NH3)inhibits its function, but ingestion promotes detoxification. Expected to be effective as part of the Natural Moisturizing Factor(NMF)of the stratum corneum.
アラニン(C3H7NO2: 2-Aminopropanoic acid); It is a synthetic raw material for sugar and has the energy generation function of the living body. The action of secreting the hormone Glucagon(Peptide hormone: 29 amino acid; In the Liver, it activates protein kinase a through binding to specific receptors and cyclic adenosine monophosphate (AMP: cAMP-dependent protein kinase (Protein kinase A); Protein kinase(Phosphorylating enzyme)) production., which is secreted when blood sugar concentration is low and promotes the breakdown of glycogen(C6H10O5)n: Discovered as a liver component by Mr. Claude Bernard in Burgundy, France in 1856.
アスパラギン酸(C4H7NO4: Aminosuccinic acid, asparagic acid; The role of increasing the absorption of K and Mg and decomposing and promoting lactic acid. Located closest to the TCA cycle of the body, which is the place of energy production.)
グルタミン酸(C5H9NO4: 2-Aminopentanedioic acid); In animals, it can be synthesized from non-essential amino acids, that is, other organic compounds. Discovered by Mr. Karl Heinrich Leopold Ritthausen in 1866 in the acid hydrolyzate of gluten, a wheat protein.It is famous as a raw material for glutathione and GABA (4-aminobutanoic acid). It can be biosynthesized from “2-Oxopentanedioic acid" and "ammonia(NH3)”. It conveys information to nerves by binding to and activating N-methyl-D-aspartic acid (NMDA) -type receptors. D-serine(It has the enzyme serine racemase (SRR) synthesized by Glial cells(It acts to give an energy source to nerve cells in the brain and builds an energy environment: A cell that fills parts of the brain other than nerve cells and supports the functions of nerve cells from various aspects.)located in a specific region of the hippocampus.)regulates stimulus volume. It is believed that the Synapse connection will be strengthened, giving memory and learning. There seems to be a hypothesis that the diseases alzheimer dementia and amyotrophic lateral sclerosis are caused by too much stimulation of the “NMDA receptor”.)
グリシン(C2H5NO2: Aminoethanoic acid); In the Nerve system, it also functions as an amino acid (Collagen: Protein, Elastin(Elastic fiber), Keratin(△Cystine), Sericin(C30H40N10O16)), which is mainly responsible for inhibitory synaptic transmission between the brain stem and spinal cord. The feature is that there are no stereoisomers(The opposite sex with different three-dimensional directions of atoms in space.)such as D-form and L-form. Not only does it improve the shelf life of food, but it also has a sweet taste and is used as a seasoning. Porphyrins(Porphyra; Hemoglobin as an oxygen carrier in human blood (Erythrocyte) is prominent.) related to the function of carrying oxygen in the blood and creatine(C4H9N3O2; A small amount in the brain.)essential for muscle exercise.
プロリン(C5H9NO2,SMILES: OC(=O)C1CCCN1); The main composition of collagen(Protein; A polymer compound formed by linking (polymerizing) a large number of 21 types of amino acids in a chain: Hydroxyproline(C5H9NO3)), which is abundant in gelatin and animal skins.
セリン(C3H7NO3: 2-Amino-3-hydroxypropionic acid); A raw material for Phosphatidylserine(C13H24NO10P, Phospholipid- Signal transduction), a component of cell membranes. It is one of the important moisturizing ingredients to maintain the moisture content of the skin, and can be a raw material for “glycine” that is close to the same ingredient. It is the Natural Moisturizing Factor (NMF: Small molecules such as Amino acids, pyrrolidone carboxylic acids (and their salts), urea, mineral salts, organic acids (and their salts).) of the skin and is the most abundant in amino acid.
ABA; [S-(Z,E)]-5-(1-Hydroxy-2,6,6 -trimethyl-4-oxo-2-cyclohexen- 1-yl)-3-methyl-2,4-pentanedienoic acid: Regulates cell protection against water balance and osmoregulation.
Monoethanolamine; C2H7NO: A substance that mediates between substances that have different surface tensions and do not mix with each other, such as water and oil, and makes them into a dissolved state≒ One of the raw materials for surfactants.
カリウム: K; adult: Potassium: It interacts with “sodium”, which is abundant in extracellular fluid. It works to maintain the osmotic pressure of cells and retain water. After ingestion and absorption in the small intestine, it is transported to tissues throughout the body, most of which is excreted by the kidneys. It is maintained by regulation of reabsorption in the kidney, and the k concentration in blood is maintained between 3.6 and 4.8 meq / l. Together with sodium, it maintains cell osmotic pressure.It works to suppress nerve stimulus transmission, functional regulation of heart and muscle, and intracellular enzyme reaction(I have to add proton transfer equilibrium). I heard that about 200g is contained in the body of an adult.
カルシウム: Ca; In the body, the amount in cells and blood is strictly controlled. Tendency to move from bone to blood as needed. About 99% is stored in bone, but also in the blood of cells and muscles. If you don't get the calcium you need, you risk mobilizing large amounts of calcium in your bones and weakening your bones. To maintain normal blood calcium levels, it is necessary to take at least 1000-1500 mg daily.Parathyroid hormone(PTH)and Thyrocalcitonin(Made by the cells of the thyroid gland, hormones have the function of lowering the calcium concentration in the blood by delaying the breakdown of bones.); It is made up of four parathyroid glands behind the thyroid gland in the neck. As the calcium concentration in In blood rises, the amount of hormones produced by the parathyroid glands tends to decrease. It stimulates bones to release calcium into the blood and reduces the amount of calcium excreted by the kidneys into the urine. Increases calcium absorption by stimulating alimentary canal to increase calcium absorption by promoting the activation of vitamin d in the kidneys.
マグネシウム: Mg;(Vinegar has been known to solubilize insoluble calcium (Ca) and magnesium (Mg) in food, however, the difference in solubilization ability among various kinds of vinegar has not been investigated. In this study, solubilization of Ca and Mg from coral powder and beef bone powder was compared with several kinds of vinegar. Calcium solubilization was observed to be high in grain vinegar, cider vinegar and wine vinegar, and low in rice vinegar and un-polished rice vinegar. On the other hand, magnesium solubilization was high in rice vinegar, wine vinegar and cider vinegar, and low in grain vinegar and un-polished rice vinegar. Calcium solubilization of coral powder was significantly negatively correlated with the pH of vinegar, while Mg solubilization was not. Comparison of solubilization of Ca in un-polished rice vinegar and acetic acid solution suggested that the phosphorus content was also responsible for solubilization in un-polished vinegar. These results suggest that ingredients in vinegar, as well as acidity and pH, affect solubilization of Ca and Mg from food when cooked with vinegar. Characterization of Solubilization of Insoluble Calcium and Magnesium with Various Kinds of Vinegar, Nakano Central Research Institute, Nakano Vinegar Co., Ltd. and Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University with Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology 45(11), 655-662, 1998-11-15)
リン: P;(Leakage in urine causes symptoms such as hypoproteinemia, decreased renal function, and hyperphosphatemia.)The amount of phosphorus per 1 g of protein contains about 15 mg, and the intake correlates with the protein intake. The role of combining and strengthening bones and teeth. Higher blood phosphate levels tend to make bones brittle. Calcium tends to combine and become coal in other than bones such as blood vessels and tendons. 
鉄: Fe; It is attracting attention as one of the world's three major deficient micronutrients along with vitamin A and Iodine(I2; In 1811, Discovered by burning seaweed with potassium carbonate, which is the raw material for potassium nitrate by Bernard Courtois(仏).)Non‐heme iron(Fe)(Included in vegetables, eggs and milk.); By taking it with foods rich in high-quality protein and vitamin C, the absorption rate into the body is improved. Fe shortage of women due to blood loss, a big problem for expectant mother and lactating women whose demand increases. Due to the metabolism of the body, about 1 mg of iron(Fe)is lost in adult men and about 0.8 mg in women per day. Ferritin(A globular protein complex consisting of 24 proteins.)has a role of suppressing deficiency and excess, and is also called stored Fe. About 90% of anemia is iron deficiency, which is deficient in fe, one of the important materials of hemoglobin.
亜鉛: Zn; Zinc‐deficiency symptom: A state in which the zinc concentration in the blood is below 80 μg / dL to 130 μg / dL. Dermatitis, stomatitis, alopecia, pressure ulcer due to lack. Loss of appetite, developmental disorders, hypogonadism, susceptibility, dysgeusia, anemia, infertility, etc. Various symptoms occur and tend to improve with zinc supplementation.
銅: Cu; It has been known for a long time as a trace essential mineral, which is present in the human body at about 80 mg. It binds to proteins and plays a role in catalyzing a wide range of in vivo reactions. Tendency to be mainly present in bone, skeletal muscle and blood. Although it is involved in hematopoietic function as well as Fe, no reports have been heard regarding the adverse effects of chronic overdose, except for some diseases. Monovalent compounds exist as insoluble salts and complex salts. Divalent salts and complex salts are common. It is absorbed from the small and duodenum and transported to the liver through the portal vein. I hear that the lower the intake, the higher the absorption rate, and the higher the intake, the lower the absorption rate. Large amounts of divalent iron and tin ions competitively inhibit the absorption of copper from the gastrointestinal tract. Inborn errors of copper metabolism(Wilson’s disease): Protein binding: Hepatolenticular degeneration. It acts as a Cu enzyme and acts as a catalyst for various reactions such as O2 transport, electron transfer, redox, and O2 addition. Important for Fe metabolism and transport, removal of active oxygen, and metabolism of neurotransmitters. Deficiencies can result from hereditary malabsorption or are acquired, but are not found in the normal life of healthy people. On the other hand, cases of symptoms are given to Babies whose main source of nutrition is low-content milk.Insufficiency may cause anemia, leukopenia, and bone abnormalities that do not respond to Fe administration. In addition, there are decreased immune function, cardiovascular abnormalities, and abnormal cholesterol and glucose metabolism. However, this is less frequent.
マンガン: Mn; Functions as an enzyme activation and a component of metal enzymes. It is a silver-white metal with an atomic number of 25 and an atomic weight of 54.94, and its surface is oxidized in the air. I hear that 12(For a weight of 70 kg)to 20 milligramme is present in the body of an adult. It acts directly with many elements, gradually reacts with water, and is easily dissolved in acids. Absorbed by inhalation, oral or transdermal: Ingested from the diet, it dissolves as divalent by gastric acid and becomes trivalent by the oxidative mechanism of intestinal cells. It is absorbed, transported to the liver through vena portalis, secreted from the bile into the intestinal tract, and mostly excreted as feces. Since absorption competes with Fe, manganese tends to be less likely to be absorbed if the iron content in the diet is high. It is abundant in mitochondria, and is contained in high concentrations in pigmented areas in the body such as the retina, hair, and skin pigmented areas. It suggests specific and non-specific effects on many enzyme activities such as oxidoreductase, hydrolase, dehydrogenase, and transferase. It is also a component of arginine-degrading enzyme, lactate dehydrogenase, and manganese superoxide dismutase (MnSOD). Examples include connective tissue and bone formation, inner ear growth formation, glucose tolerance, fertility, lipid metabolism, growth and involvement in brain function.
モリブデン: Mo; In the human body, it acts as a component of the molybdenum enzyme that catalyzes the redox reaction. I've heard that hypervitaminosis is not a problem because it is relatively less toxic than other heavy metals. It dissolves in hot concentrated sulfur acid, but does not react with H2O, hydrochloric acid(HCl), and dilute sulfuric acid(H2SO4)and does not dissolve. It is abundant in the liver and kidneys in the body and tends to be easily absorbed in the stomach and small intestine. Xanthine oxidase(NAD+-xanthine dehydrogenase), aldehyde oxidase, and sulfite oxidase are known as constituents. Insufficiency often causes tachycardia, hyperventilation, night blindness, etc. due to long-term complete parenteral nutrition.However, I heard that the administration is expected to improve the symptoms. In healthy people, hypervitaminosis is not a problem in a normal diet because it is excreted quickly even if it is ingested excessively. Chronic poisoning can cause gout-like symptoms such as joint pain and hyperuricemia. Acute poisoning can cause gastrointestinal disorders with diarrhea, leading to coma and heart failure. It is abundant in cereals, legumes and nuts.
クロム: Cr; Usually, it is in the state of trivalent chromium and hexavalent chromium. Although its content in food is extremely low, it is involved in the metabolism and maintenance of sugars, cholesterol, connective tissue and proteins in vivo. It does not rust in the air or water, but what is interesting is that it dissolves in hydrochloric acid and dilute sulfuric acid. It is absorbed mainly in the small intestine, but its intestinal absorption mechanism has not been clarified. The only mineral whose content in the body decreases with age. Complete venous nutrition that does not contain it or high-calorie infusion may cause impaired glucose tolerance. However, there is room for improvement of symptoms by supplementing Cr chloride. Insufficiency may lead to decreased insulin sensitivity, abnormal nitrogen metabolism, weight loss, peripheral neuropathy, stupor, and corneal disorders.
セレン(selenium : Se(34),1817); It exists bound to protein, and its absorption is thought to occur at the same time as protein absorption. A component of glutathione peroxidase(Isoenzyme)that decomposes hydrogen peroxide(H2O2)and hydroperoxidase(-OOH). Important for antioxidant systems, along with vitamin E and superoxide dismutase (SOD). I also heard that it is a component of enzymes involved in ascorbic acid(C6H8O6)regeneration, thyroid hormone activation and metabolism. It seems that there is about 250 μg per kg of body weight in the human body. Homeostasis is maintained by excretion into the urine. Insufficiency is thought to cause cell damage due to peroxides. However, it seems that there are almost no problems with normal eating habits in Japan. Selenium is abundant in algae, seafood, meat, and egg yolk.
【効果効能】
抗癌作用: Anti-cancer effect 
抗酸化作用: Antioxidant effect
抗菌作用: Antibacterial effect
抗腫瘍性: Anticancerous
肩こり: Stiff shoulder
腰痛: Lumbago
髪の毛健康: Hair health
風邪予防: Prevention of cold
美肌・美容: Beautiful skin and beauty
老化防止: Prevention from getting older
ダイエット: Diet
むくみ解消: Edema
利尿効果: Diuretic effect
女性ホルモン: Female hormones
妊婦: Expectant mother
貧血: Anemia
疲労回復: Recovery from fatigue
視力維持: Maintaining eyesight
消化促進: Digestion promotion
殺菌効果: Bactericidal effect
骨粗しょう症: Osteoporosis
新陳代謝: Metabolism
ストレス解消: Stress relief
活性酸素抑制: Reactive oxygen species suppression
喉・呼吸器安定: Throat, respiratory stability
皮膚粘膜強化: Skin and mucous membrane strengthening
高血圧: Elevated blood pressure
肥満: Corpulence
生活習慣病: Life style related disease
血中コレステロール緩和: Blood cholesterol relief
コレステロール: Triglycerides  
二日酔い: Overnight drunkenness
心筋梗塞: Heart infarction
脳梗塞: Brain infarction
血栓予防: Thromboprophylaxis
食欲不振: Anorexia 
精神安定: Tranquilize
胃潰瘍: Gastric ulcer
胃腸障害: Gastrointestinal injury
Photo_21-07-25-06-41-24.946~2.jpgPhoto_21-07-25-06-41-32.568~2.jpgPhoto_21-07-25-06-41-34.696~2.jpgHOLICC SHOP【HB】

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