In order to produce 高品質 and 美味しい蜜柑, it is necessary to thoroughly manage 栽培 such as temperature and 水管理, and behind that, there is 昼夜の作業 of the 生産者 and dedicated efforts, and in the 夏 Greenhouse the temperature is 重き作業 in it is unimaginable and difficult.




【製品名(商品名)】
グリーンハウスみかん
【種類】
Citrus unshiu (Swingle) Marcow.
【生産地】
長崎県長崎市, 諫早市, 西海市, 西彼杵郡時津町, 長与町(JA長崎せいひ)
【名前の由来】
Cultivated in a slightly heated greenhouse Named after the Citrus unshiu.
【主な特徴】
“Agricultural cooperative Nagasaki-Seihi”, Located in southwestern Nagasaki prefecture. The main agricultural products are Mandarin oranges(Production accounts for about 60% of the prefecture's production), which make up the majority of the prefecture's produce, and Loquat, which boasts the highest production volume in Japan. JA original brand of beef cattle “Dejima-Barairo”: 2012-第10回全国和牛能力共進会: Japan's number one and highly rated by the market. “Nagasaki Japanese beef cow”, Producers registered in the Nagasaki Wagyu Producer Registration System. It's defined as a generic term for Japanese beef produced for the purpose of fattening. It can be raised with great care and affection in a blessed natural environment, which is relatively cool in summer and relatively warm in winter. The origin of Wagyu beef in Nagasaki is old, Bovine bones and teeth from the Yayoi period 2,200-2,300 years ago were discovered from archeological sites in Nagasaki Prefecture. Since it is an introduction to Nagasaki, I will introduce it from a city that I have a deep feeling for (although it is not in the jurisdiction). “Nagasaki City”, In the southeastern part of Nagasaki, people lived by hunting and fishing from the Jomon Period to the Yayoi period and the Kofun Period about 6000 years ago. Relics from the Jomon period have been excavated from 田上名 and 本郷名, and relics from the Yayoi Period have been excavated from the precincts of Mt. Matsuo Muryo-in Gyokudaiji Temple(浄土宗; 理残公)and 千々名. In terms of culture, it is said to have been influenced by China and Korea for a long time. From now until about 800 years ago, it was called "Toyagaura", including the islands scattered from Tomachi to the southern mothers, centering on Fukahori. From the end of the Kamakura period, Kanto Kazusa no kuni(Corresponds to the current Isumi City, Chiba Prefecture)Fukahori went down to this place, changed the place name to Fukahori, and ruled for generations until the latter half of the 16th century. During the Edo period, it became the Fukahori branch of Saga Nabeshima, and now you can see the remains of the samurai residence that retains the remnants of that time. In the area where the Nagasaki Highway passes, there is a Kanmon Bansho, and there are still Bansho Bridges that retain their remnants. In addition, Mogi, which is the starting and ending point of the Mogi Highway, has developed as an important port connecting Amakusa, and even now, there are places that retain the remnants of those days, and it is full of charm. On the route from Kokura to Nagasaki, a series of highway landscapes over the post station and the pass are developed. Along the Hachiro River, Yagami-juku, Yagami Shrine, Honjin Ruins, and Yakuyashiki Ruins retain the remnants of the past, and the Himi Pass has a steep, broken pass. Agricultural village landscape of Funaishi : In Koga / Matsubara's Ueki no Sato, you can see a garden nurtured by the history of 400 years of planting technology. Podocarpus macrophyllus, which is 600 years old (Thunb) There are excellent things such as the dry landscape garden of Lamb. Var. Maki Sieb., The mansion garden of Gyosenkaku, and high-class potted plant. Amiba / Toishi fishing village and Makishima island landscape : Located in the inner part of Tachibana Bay, it consists of Aba fishing port, Toishi fishing port, and Makishima, and the aquaculture raft of the cove is symbolic.  Mt. Fugendake becomes a landmark of the area, and the natural coasts such as the rocky areas of Makishima, offshore islands, and Louis XIV rocks of Amiba, and the stone-framed embankment of Toishi fishing port shine in the area. Mogi townscape : The main streets of Wakana Bridge and along the Mogi Kaido, which once prospered in the inn town, are lined with townhouses, mansions, and warehouses with shutters, forming a simple and attractive town, and a scenic harbor. The river mouth is impressive. Mogi loquat is planted in a stepped field on a steep eastern slope of the Nagasaki Peninsula, and in early spring, the scenery of wearing a bag of fruits develops as if white and yellow flowers bloomed in the spread of Amakusa Nada. Fukahori samurai residence : As the site of the Nabeshima clan castle town in the Fukahori territory of the Saga domain, the medieval and early modern land divisions, digging divisions, and clan ports remain. The townscape of the samurai residence can be seen, and the town division is important as an indication of the connection with the Saga domain. Nagasaki Port, which forms the center of the city today, was opened in 1571 by Mr. Omura, who unified the local samurai who had been assigned to the Nishisonogi area, with Fukaeura as the gateway to foreign trade. After the 1639 Sakoku Ordinance was issued, it will have the privileged status of being the only open port open overseas in Japan. Dejima, where the Dutch trading house was located, contributed greatly to the modernization of Japan as a window for trade with Europe and for academics and culture in Western Europe. In 1859, when the Shogunate allowed free trade, the area from Oura to Dejima was created as a foreign settlement.  Especially in the Higashiyamate and Minamiyamate districts, many Western-style buildings such as Oura Catholic Church, Glover House, and Ringer House are preserved, and the scenery that makes you feel exotic is still exciting. It is said that in the modern era, the industry centered on shipyards has developed by taking advantage of the good natural ports. The shipbuilding industry became the main industry of Nagasaki City as the Nagasaki Steel Works, which was completed in 1861 and originated from the “Navy Training Center” established in 1855, was acquired by Mitsubishi in 1887 to expand its business. It was decided to grow. Landscape of Dejima during the isolation Period, landscape of Tojin Yashiki : It is a historical remains that shows that there was a window for international exchange in the isolation system, and some buildings and the surrounding stone walls on the south side are currently being restored. The waterside of the Nakashima River is dotted with Ishibashi bridges from Fukurobashi / Meganebashi to the Futami River. The riverside sidewalks are well maintained and offer a good waterside landscape. The waterside area of ​​the Doza River is famous as the place where Dejima, Shinchi, Nagasaki Kaisho, Satsuma feudal lord's residence, etc. were once established. Landscape of the remains of the town building during the Uchimachi and Tomachi periods : The Ishigaki group that remains outside the street between the prefectural office and the city hall is a valuable historical remains that tells the process of formation of the former town of Nagasaki, and conveys the history of the three generations of Edo, Meiji, and modern times to the present day, and makes it a cityscape. Gives a personality and satisfies the glitter. Townscape and landscape of temples and shrines and Chinese temples that required Suwa Shrine : Surrounding the town of Nagasaki, there are a series of temples and shrines at the foot of the mountain, and To-ji are scattered around, creating a quiet, solemn and stately atmosphere. Machiya architecture group and landscape of Kunchi festival(It is a festival dedicated to thank the harvest and is the name of the autumn festival in northern Kyushu.): Many buildings such as townhouses, merchant houses, restaurants, and mansions can be seen in the former Maya district centered on Nakadori and the Nakashima River opposite bank, oil shop district, and Maruyama District. Machiya in the Odori-cho area can be seen in between the Nagasaki town building and the kunchi event that is still popular today. Former Maruyama Yukaku; red-light district restaurant, number check, cobblestone townscape : There are many buildings with excellent designs such as the Fukusaya(Founded in the first year of 1624, Castella head family) at the entrance and Kagetsu, Aoyagi, and the number check where you can feel the remnants of the prostitution quarter. Settlement landscape of Oura, Higashiyamate, and Minamiyamate during the opening period : Many Western-style buildings built in the early modern period remain on coastal streets, carriageways, slopes, and Yamate streets. In addition, temples and shrines are built in the area of ​​Oura Catholic Church, and buildings of different religions are close to each other. Landscape around Nagasaki Port and the port from Yamate (Mt. Inasa, etc.) : The Uragami and Nakashima rivers pour into Nagasaki Port, which has a sense of depth from north to south, and you can see a variety of landscapes according to changes in tide level, season, and time. In addition, it has an excellent view from the mountains and hills surrounding Nagasaki Port, such as the Megami Large Bridge(Cable-stayed bridge on Prefectural Road No. 51 Nagasaki South Circular Line and Rinko Road Megami Ohashi Line.)at the port entrance and the seven high mountains of Nagasaki. The northwestern region is famous for the arrival of Portuguese ships from 1565 to 1570 before the opening of the port of Nagasaki. During the Edo period, there was a platform for monitoring foreign ships entering Nagasaki. It is a district where the Urakami Highway passes, and it is said that the bansho as the entrance to Tenryo Nagasaki was set up around the present Chitose Town, and it was the cornerstone of transportation. The Sino-Japanese War broke out in 1937, and after entering World War II in 1941, an atomic bomb was dropped in 1945. Under the slogan of “Peace from Nagasaki”, the site of the drop was a collection of purified goods from Nagasaki citizens, various parts of Japan, and other countries, and in August 1955, a peace prayer statue and a peace park were constructed. Townscape from Mt. Iwaya : It is one of the seven high mountains of Nagasaki and has been worshiped as a mountain of worship since ancient times.  From the summit of 475 m above sea level, you can see east and south, and from the vicinity of Akasako, you can see Nagasaki city, Inasayama, Nagasaki port, Koyagi, Io Island, and if the weather is nice, Unzen and Amakusa. It is known for its rich nature, where you can feel the topographical features of Nagasaki in the basin. Fault coast and fishing port on the Kakuriki Nada : In the steep fault scarp area, capes and coves alternate in and out, and the beauty of nature is excellent. Especially at dusk, the small islands floating in the sea shine in the setting sun, creating a beautiful sunset landscape. In the cove, there are fishing villages such as Shikimi, Teguma, Oe, and Koura, which are characterized by the shape of the river port. Among them, the Nagasaki fishing port is one of the leading bases for the production and distribution of marine products. Landscape of Peace Park / Atomic Bomb Fall Center and A-bombed Remains : It is a historical place that symbolizes a rare event in human history, such as the dropping of an atomic bomb on a city, and is a place that seeks the abolition of nuclear weapons and peace and becomes the face to send to the world as a peaceful city. The Kinkai district is located in a scenic spot facing the quiet Katagami Bay and Muramatsu Bay, and has ancient ruins and a mountain castle from the end of the Middle Ages. For 300 years from the end of the Warring States period to the Meiji period, it belonged to the domain of Mr. Omura, who was a Christian Daimyo, and belonged to Nagasaki prefecture after the abolition of the domain. From Tone facing Nagaura to Nagaura, which leads to Oguchi Seto to Omura Bay, there is a Jishoji temple where Mr. Migeru CHIJIWA's 従兄弟 Marina connected hermitage, Shiogama Shrine, Sansha Shrine, Nagaura Cemetery Olympic Tower, etc. Historical historic site remains. In addition, there are stone masonry slopes using heated stones and masonry groups of masonry walls scattered around, and you can see sloped houses where you can feel the lifestyle culture of the time. Livelihoods such as “Nagaura watermelon”, pearl farming, and stone industry have prospered. From the latter half of the 1970s, residential land development progressed as a commuter town in the city center, and it developed as a settlement base blessed with a good natural environment. In addition, the population has increased accordingly. Coastal landscape of Katagami Bay and Omura Bay : There is a wide variety of scenic beauty, such as the distant view of Omura Bay seen from the middle of the mountains and the Odo Peninsula, the shape of the bay from all over the hills along the coastline, and the view of the opposite bank from the coastal road. Hojuzan Jishoji Temple (the Nichiren sect of Buddhism) Built in 1658 by the chief retainer of the Omura domain, Yasumasa ASADA-Ko, to mourn the bodhi of the Grandmother Jishoin; Baptismal name: Donna Mariina. The Asada family is a family that has been in the important position of the Omura clan chief retainer for generations) And the landscape of the masonry settlement : Historical sites are gathered, and you can see the Jishoji temple, Shiogama Shrine, Sansha Shrine, and Nagaura Cemetery Gorinto, where Mr. Migeru Chijiwa's cousin Marina connected hermitage. You can see a village with a masonry slope made of warm stones and a masonry wall. Nagaura-Odo agricultural and fishing village landscape : House cultivation that makes the best use of the few flatlands and gentle slopes is often seen. In the rias-style peninsula of Odo, terraced fields with warm masonry stone walls develop, and the pearl farming fishing villages and the landscape of paddy fields by the sea shine. Sotome District : There are many cultural assets such as ancient ruins such as Shitsu ruins and Miyata burial mounds, medieval Kamiura-related historic sites, modern Omura clan-related historic sites, modern social welfare and religious historic sites, and so on. The Christian culture remains strong around. Christian culture remains strong around Shitsu and Kurosaki. In Kamiura, ancient cultures such as temples built in the early Edo period and shrines with a long history are concentrated. In particular, the history of Christianity is one of the cultural characteristics of the Sotome district, along with the activities of the French missionary Father de Rotz during the Meiji era. In addition, there are resources such as rice terraces in Onakao, stone houses in Makino, and stone walls in Maruo, which are reminiscent of life at that time. Matsushima Coal Mine Co., Ltd. started coal mine development in Ikeshima in 1952, and started commercial coal production in 1959. It has evolved from a semi-agricultural and semi-fishing village to a town whose core industry is the coal industry. However, in November 2002, the Ikeshima Coal Mine, which was the last coal mine in Kyushu, closed. Nomozaki District(A town in Nishisonogi District by 2005) : Located at the tip of the Nagasaki Peninsula (Nagasaki Peninsula), the southernmost tip of the mainland of Kyushu, the northwestern part passes through the Goto Nada and overlooks the Goto Islands. The southwest is overlooking the East China Sea, which is the eastern China Sea, and the east is surrounded by the sea on three sides facing the Shimabara Peninsula and the Amakusa Islands, overlooking Tachibana Bay and Amakusa Nada. In Nomozaki, where you can see the scenery from a panoramic view, a Tomi Bandokoro was set up to monitor the entry and exit of foreign ships during the isolation period. In addition, important ports such as Kabashima, Wakimisaki, and Takahama were designated as Tenryo (directly controlled by the Edo Shogunate). The Kanonji road from Kanonji, which is said to have opened “Gyoki”-Ko in 709, to Nagasaki is used for smuggling of Nagasaki merchants, and many relics that are said to have been donated by them are left at Kanonji. Sanwa District : Set net fishing has been active for a long time, centering on the Kayaki and Tameshimachi fishing ports, and the lively Kayaki yellowtail and blackberry mussels are famous. In recent years, aquaculture has become the mainstream, and it seems that it has changed from “fishing to catch” to “fishing to grow”. Kayaki smithing, which is said to have started in the Edo period, is a notable traditional craft in the area. A disciple of Yoshida Samanokami Naotane-Ko, a swordsmith at the time, used mosquito-fired water and clay that are suitable for quenching blades. We made good quality cutlery, and it became popular for generations. Today, four blacksmith craftsmen continue to follow traditional techniques, and along with the Nanban board, the specially patterned kitchen knife “Wazamono; sharp sword” is a special product. The place name Koyagi is said to be derived from the legend of Koyagi 弘法大師. Originally, it consisted of two islands, Koyagi Island and Kagenoo Island, and during the Tokugawa period it was the territory of the Saga Domain, the Nabeshima branch domain, and Fukahori. Since the Meiji era, the coal and shipbuilding industries have been declining, and the population during the peak period (during the war) was over 20,000. However, due to changes in the socio-economic situation after the war, shipbuilding disappeared in 1955 and coal disappeared in 1964, and it became stagnant. The prefecture reclaimed the Koyagi Fukahori area for seaside industry from 1966 to 1971, and Mitsubishi Heavy Industries, Ltd. acquired the former shipyard facility in 1967. In 1972, it was revived by starting full-scale operations with the completion of the state-of-the-art factory. During the isolation period, the place where the Dutch ships and Táng ships that entered and exited Nagasaki Port from Tomidake on Iojima Island were watched. The Iojima Lighthouse, located at the northernmost tip, was installed at eight locations nationwide when the Edo Treaty was signed with the four countries of the United Kingdom, the United States, France, and the Netherlands in May 1866, at the end of the Tokugawa Shogunate, one. This is considered to be the first valuable structure in Japan for an iron-built Western-style lighthouse. In the modern era, the population increased rapidly due to the opening of the coal mine in 1941.  However, the coal mine that led to the island's prosperity closed in 1972 and the population plummeted. In recent years, the resort facilities have been expanded since 1989, taking advantage of the scenic and abundant nature and the gentle climate rich in humanity, and it is loved as a resort island. It is said that the Heike Ochimusha settled in 1185, and then in 1695, a person named Mr. Goheita discovered coal. With the help of Mr. Fukahori, it was commercialized from around 1710, and the curtain of the coal mine era in Takashima was opened. It seems that the Takashima Coal Mine began full-scale operation in 1868 when Mr. Thomas Glover began development as a joint venture with the Saga Domain. He dug a shaft 43 m deep and used a steam engine to mine coal, which was called the “Hokkeiseiko” and was the first Western-style shaft in Japan. After that, the coal mine was transferred to Mr. Yataro IWASAKI of Mitsubishi Corporation in 1881, and the operation under the management of Mitsubishi began. Since then, Mitsubishi is said to have expanded its business and prospered based on the profits obtained from coal mined in Takashima. Therefore, it is well known that it is said to be one of the birthplaces of Mitsubishi. ‘Isahaya City’, It is located almost in the center of the prefecture. It faces three seas with different characteristics: the tidal flat Ariake Sea in the east, the inland sea Omura Bay in the west, and the open sea Tachibana Bay in the south. The Honmyo River is the only first-class river in the prefecture that flows through the beautifully towering mountains of the Tatara Mountains and the central part of the city. Downstream of it is a vast reclaimed land, blessed with a rich and diverse natural environment. The Isahaya Plain, formed by reclamation for more than 400 years, is the largest breadbasket in the prefecture. The fertile hills are a specialty of vegetables, strawberries and mandarin oranges. It has an industrial park, which is one of the prefecture's leading industrial clusters, and has the second largest shipment value of manufactured goods in the prefecture. One city and five towns merged on March 1, 2005. We are promoting town development aiming at the realization of “Isahaya, a creative city where humans shine”. It is warm all year round, with little winter snow, and has a good balance of rich nature and transportation access. With a total area of ​​341.79 km2, annual average temperature, about 16.4 ° C, annual precipitation of about 2,329. The oldest archaeological sites in the city include the Nishiwakudo site (Tsukuba Town), the Takano site, and the Kakizaki site (Kaizu Town), which are located in the southern part of Omura Bay. It is a Paleolithic site, which corresponds to the period of knife-shaped stone tool culture from about 30,000 years ago to about 15,000 years ago. The Jomon Period began about 10,000 years ago, when the scope of hunting and food was expanded by the invention of bows and arrows and pottery. The Kawgashira site (Yunoo Town) is located at an altitude of about 360 m, and two residences in the early Jomon period were discovered, revealing the state of life in the mountains. Uki Shell Mound (Matsusato Town) is a shell mound from the middle to late Jomon period overlooking Tachibana Bay. It was excavated by Dr. Kosaku HAMADA of Kyoto University in 1925, and is said to be the birthplace of Nagasaki archaeological studies. The Ikiriki Ruins (Tarami Town) is located in the inner part of Omura Bay, and is known as one of the leading ruins in the prefecture representing the early Jomon period about 6,000 years ago. During the Yayoi period, waves of new culture such as rice cultivation and metalware rushed from the continent, making a big leap from the traditional hunter-gatherer society, and food production began in earnest. One of the new cultures is the burial method called dolmens, but there are the Hukantake dolmens (Warigoi Town) and the Izaki dolmens (Konagai Town) in the city. In the Kofun period, tumuli were built along the coasts of the Ariake Sea and Tachibana Bay. Zenjinsan tumulus (Takaki Town), Omine tumulus and Nagatoonizuka tumulus (Konagai Town) are tumuli with horizontal hole type stone chambers. The Omine tumulus is famous as the only tumulus in this prefecture with a stone shelf in the stone chamber. The Taika Reform in 645 drastically changed the structure of the nation, and the government centered on the emperor directly controlled the land and people throughout the country(complete state ownership of land and citizens System (proclaimed by the Taika reforms) (Ritsuryo period)). The biggest project was the implementation of the group field system, which was a grid-like division of land to facilitate the provision of Kubunden; land distributed to all citizens from which yields were taxed by the government and tax collection. Traces of this remain at the Taibarujori site (Nakaoki / Saiwai Town), Onojori site (Munekata / Nagano / Kawauchi Town), and Tayuijori (Iimori Town). In the Nara period, the Ritsuryo government established a station road on which fast horse runs and a station house, which is the connecting organization, in order to maintain close communication between the central and local areas. According to the "Engi-shiki", there are four stations in Nagasaki prefecture: 新分 (Sonogi District), Funakoshi, Yamada, and Wild Bird (Takaki District), and it is assumed that “Funakoshi” was in Funakoshi Town. In the Kamakura period, “Isahaya Village” first appeared in the document “Yawata Usa Shrine Okagami; 八幡宇佐宮御神領大鏡”, which is said to have been made around 1197 and is stored in Usa Jingu, Oita Prefecture. It is written that Miyatoki FUJII-Ko, the main lord of Isahaya Village, donated this region, which was originally a public territory, as a villa of Usa Jingu at the end of the Heian period. During the period of conflict between the North and South Dynasties, the villa forces have completely disappeared, and a fierce change of lords is taking place. On the south side of the Umoretsu River, Mr. Saigo, whose residence is Uki Castle, is in the Southern Court, and on the north side, Mr. Isahaya, whose residence is Funakoshi Castle, is in conflict with the Northern Court. The North-South dynasty was united in 1392, and then Naoyoshi Saigo-Ko appeared at the beginning of the Warring States period. The world of fierce Warring States was put to an end. After that, Mr. Saigo will rule this region for about 100 years until the beginning of the Edo period. Mr. Saigo built Takaki around 1474, and to prevent the invasion of foreign enemies, he built branch castles such as Oki Castle (Nakaoki Town), Ejo (Moriyama Town), Masaki Castle (Masaki Town), and Furuta Castle (Zenjuji, Takaki Town). I built it. He has excellent civil engineering skills and has been working on irrigation canal maintenance, reclamation. By the time he was a grandson, Sumitaka-Ko became a powerful family alongside Mr. Arima of Shimabara, Mr. Matsuura of Hirado, and Mr. Omura. After that, Hideyoshi-Ko gave Ieharu Ryuzoji-Ko of Chikugo-Yanagawa a red seal of 22,000 stones of Isahaya area because Nobunao Saigo-Ko did not obey the order of Hideyoshi-Ko's capture of Shimazu in 1587. Ieharu-Ko urged Mr. Saigo to surrender Takashiro, but he did not obey it, so he attacked Takashiro and Mr. Saigo routed toward Shimabara. After that, Mr. Ryuzoji changed his surname to “Isahaya” and the era moved to the Edo period. The Saga domain was originally the territory of Mr. Ryuzoji, but in 1607 the Saga domain was established with Katsushige Nabeshima-Ko as the first generation. Mr. Isahaya was in the position of “kinship apposition; 御親類同格” and played a part in the feudal affairs as “Saga domain Isahaya territory” for about 260 years until the Meiji era. The Isahaya area at that time was almost the same as the current Isahaya city, except that part of Tarami Town was included in the Omura Domain. The Saga domain carried out three-part landing twice in 1610 and 1621 for financial reconstruction, and the initial 22,000 koku decreased to more than 10,000 koku. In addition, the control system for Isahaya territory has been strengthened politically and economically by establishing the Saga magistrate's office. Floods frequently occurred in the Honmei River, and many lives were lost, especially in the floods of 1699, and the following year, a drought struck. In memory of the victims of these disasters, the 7th lord Shigeharu-Ko carved 500 Arhats in Bucheon. Even under these circumstances, the wisdom and high technical capabilities of the worshiping ancestors Isahaya were demonstrated everywhere. Newly reclaimed rice field development by reclamation was actively carried out, and Mr. Noriyoshi Yamazaki (Kawauchi Town), Mr. Matsumoto Siro Saemon (Iimori Town), Mr. Jinemon Jinno (Moriyama Town), etc. left great achievements and became a major foundation of today's agriculture. In addition, the Meganebashi Bridge, which was bridged in 1839, was completed as a result of the people's long-cherished desire to create a bridge that never flows and the advanced technical capabilities of an arch-type stone bridge. The Nagasaki Highway, which was established in the early Edo period, connects Nagasaki and Kokura to Nagasaki, Tarami, Isahaya (Eisho-juku), and Omura. Also, with Isahaya as a turning point, there were Tara Highway and Takezaki Kaido from Takaki (Yue-juku) to Konagai, and Shimabara Highway to Moriyama. Isahaya has prospered by taking advantage of its geographical conditions as a transportation hub where these land and sea routes are concentrated and passed. City Designated Cultural Property : 有形文化財/ 建造物 : 島原の乱戦没者追悼碑, 西小路町, 昭和54年4月1日,有形文化財/ 建造物 : 愛宕山の肥前鳥居, 宇都町, 昭和56年8月28日, 有形文化財/ 建造物 : 愛宕社宝殿と三重塔, 宇都町, 昭和60年1月31日, 有形文化財/ 建造物 : 旧早川家住宅, 小野島町 ,平成5年7月23日, 有形文化財/ 建造物 : 化屋/ 阿蘇神社の二の鳥居と三の鳥居, 多良見町, 平成10年7月3日, 有形文化財/ 建造物 : 十六善神社の一の鳥居と二の鳥居, 多良見町, 平成10年7月3日, 有形文化財/ 建造物伝 : 「円通寺」跡の石塔群, 多良見町, 平成10年7月3日, 有形文化財/ 建造物 : 井樋尾「御境石」多良見町, 平成11年7月27日, 有形文化財/ 建造物 : 化屋名塩浜跡石碑, 多良見町, 平成11年7月27日, 有形文化財/ 建造物 : 慶師野の将棋墓, 森山町, 平成14年4月3日, 有形文化財/ 建造物 : 西川内堤改修記念碑, 多良見町, 平成16年4月26日, 有形文化財/工芸品 : 肥前長崎の焼物, 東小路町, 平成19年2月1日, 有形文化財/ 彫刻 : 市杵島神社の馬頭観音, 小長井町, 昭和52年9月26日, 有形文化財/彫刻 : 金泉寺の千手観音像, 高来町, 昭和62年3月2日, 有形文化財/ 彫刻 : 田結観音寺の聖観世音菩薩像, 飯盛町, 平成3年5月21日, 有形文化財/彫刻 : 唐比権現の神像と仏像, 森山町, 平成15年8月11日, 有形文化財/ 彫刻 : 旧荘厳寺木造阿弥陀三尊立像, 金谷町, 令和元年11月1日, 有形文化財/絵画 : 江の浦/ 熊野神社の天井絵と絵馬, 飯盛町, 昭和63年12月20日, 有形文化財/ 絵画 : 諫早家歴代肖像画, 西小路町, 令和元年11月1日, 有形文化財/ 絵画 : 林公琰肖像画, 飯盛町, 令和元年11月1日, 有形文化財/ 石造 : 物代官モクどんの石棺, 小長井町, 昭和52年9月26日, 有形文化財/石造 : 物唐比権現石塔群, 森山町, 平成15年8月11日, 有形文化財/ 歴史資料 :唐比のくり舟, 森山町, 昭和56年7月14日, 有形文化財/ 古文書 : 高屋家文書, 多良見町, 平成12年8月23日, 有形文化財/ 古文書 : 円満寺の東照宮様寺法拾五ヶ条御垂範, 多良見町, 平成15年2月25日,有形文化財/ 古文書 : 化屋組記事簿, 多良見町平成16年4月26日, 有形文化財/ 古文書 : 喜々津村, 漁業組合関係書類, 多良見町, 平成17年2月18日, 有形文化財/ 古文書 : 多良嶽山観世音菩薩縁起并讃, 高来町, 令和元年11月1日, 有形文化財/ 古文書 : 太良嶽縁起, 高来町, 令和元年11月1日, 有形民俗文化財 : 天祐寺の六地蔵石幢, 西小路町, 昭和52年3月5日, 有形民俗文化財 : 田原の六地蔵石幢, 小長井町, 昭和52年9月26日, 有形民俗文化財 : 開の辻の六地蔵石幢, 下大渡野町, 昭和56年8月27日, 有形民俗文化財 : 慶巌寺の磨崖仏三十三観音, 城見町, 昭和59年7月26日, 有形民俗文化財 : 久山の磨崖仏三十三観音, 久山町, 昭和59年7月26日, 有形民俗文化財 : 水ノ浦のスクイ漁場, 高来町, 昭和62年3月2日, 無形民俗文化財 : 本村浮立と白塔掛打, 森山町, 昭和60年5月31日, 天然記念物 : 津水/ 熊野神社の植物群, 津水町, 昭和52年3月5日, 天然記念物 : 天初院のヒゼンマユミ群生地, 高来町, 昭和62年3月2日, 天然記念物 : 向島のノアサガオ群生地, 飯盛町, 平成12年1月12日, 天然記念物 : 長里/ 阿蘇神社のヒゼンマユミ群生地, 小長井町, 平成17年2月14日, 天然記念物 : 池下のアコウ, 飯盛町, 平成3年5月21日, 天然記念物 : “伊木力のコミカン”,多良見町, 平成15年2月25日, 天然記念物 : 群のクロガネモチ, 多良見町, 平成16年4月26日,名勝 : 金比羅山頂, 小野町, 昭和52年3月5日, 名勝 : 川下の牛のはなぐり, 飯盛町, 昭和63年12月20日, 史跡 : 御手水観音の磨崖仏群, 御手水町, 昭和52年3月5日, 史跡 : 善納岩陰, 湯野尾町, 昭和52年3月5日, 史跡 : 本明石棺群, 本明町, 昭和52年3月5日, 史跡 : 大村街道, 破籠井町, 昭和52年3月5日, 史跡 : 大峰古墳, 小長井町, 昭和52年9月26日, 史跡 : 城山古墳群, 小長井町, 昭和52年9月26日, 史跡 : 南平墓石群, 小長井町, 昭和52年9月26日, 史跡 : 岩宗墓石群,小長井町, 昭和52年9月26日, 史跡 : 若杉春后居宅跡, 森山町, 昭和56年7月14日, 史跡 : 善神さん古墳, 高来町, 昭和62年3月2日, 史跡 : 金泉寺の石垣と墓石群, 高来町, 昭和62年3月2日,史跡 :横津の石槨, 飯盛町, 昭和63年12月20日,史跡 : 飯盛鬼塚古墳, 飯盛町, 平成12年1月12日, 史跡 : 土橋貞恵墓地, 森山町, 平成14年4月3日, 史跡 : 陣野家墓地, 森山町, 平成14年4月3日, 史跡 : 上井牟田の歴代庄屋の墓, 森山町, 平成14年4月3日, 史跡 : 柏原古墳群, 森山町, 平成15年8月11日, 史跡 : 中里虚空蔵さん, 多良見町, 平成17年2月18日. In Nagasaki Seihi area, the cultivation calendar (improvement technology) of the area is created. The crops for which the calendar is created are as follows for each specialty (crops, vegetables, fruit trees, flowers, livestock). Prefectural Central Promotion Bureau Saikai Office(Jikibago, Seihi Town, Saikai City). Crop: Early paddy rice, normal paddy rice, normal paddy rice (granule, emulsion, wettable powder system). Vegetables: Elevated cultivation of strawberry, Sachinoka (seedling) (main field), asparagus (1st year) (2nd year and after), onion, set onion, spring broccoli, autumn broccoli, winter carrot, harvested carrot, spring Daikon, Autumn / Winter Daikon, House Nira, Spring pumpkin, Suppressed pumpkin, Forcing / semi-forcing cucumber, Summer / Autumn cucumber, Winter / Spring tomato, Mini tomato (Forcing), Summer / Autumn eggplant, Momordica charantia; 苦瓜, Sweet corn, Shishitou, fava bean, Spring onion, Suppression Ingen, Sayaendo, Broccoli, Winter cabbage, Spring cabbage, Autumn / Winter cabbage, Spring cabbage, Lettuce, spinach, Brassica juncea var. integrifolia; 高菜, Brassica junce; 勝男菜, Turnip, Fruit and vegetable onion, Tomato, Watermelon, Lotus root, Eshalot, Garlic, Okura. Fruit tree: Citrus unshiu, Midnight citrus, Kawachi Bankan in the facility, Greenhouse mandarin orange, Green house oranges, House loquat, Nashi pear, Grape, Figs, Peaches, Plum, Kiwi fruit, Persimmon, Ume, Chestnut. Flower and ornamental plants: Iwa no Hakusen, Zinba (白輪菊 shipped in November + 2 times cut, December shipping + 2 times cut, January shipping + 2 times cut, April shipping) Sei no Issei (白輪菊), Sei no Nami (summer-autumn: 白輪菊), Small chrysanthemum, Statice, Turkish ginkgo, Snapdragon, Shikimi, Stock, Sunflower, Hozuki, Eucalyptus. “Greenhouse Mikan”, The skin is green and only the fruit inside is ripe. A gem that is juicy, has a good balance of sweetness and acidity, and you can enjoy a refreshing aroma. Low-warming cultivation is almost the same as warming cultivation, but it is a method of lowering the temperature setting than warming cultivation and accelerating the growth of mandarin oranges by about 1 to 2 months compared to open-field cultivation. It does not have a strong acidity like the open-air “Aokiri Mikan(Tendency to harvest a little earlier than the very early Mikan.)”, and is a must-see for those who like sweet and sour taste. It is said that the name “Wenzhou” of Wenzhou mandarin is derived from the Wenzhou region of China. Wenzhou is famous as a production center of mandarin oranges, and it is said that the name comes from the fact that it is as wonderful as mandarin oranges. In addition, Satsuma mandarin is said to have been born in Japan, and was born in the Edo period. It seems that the mandarin orange, which had seeds at that time, was mutated and became seedless, and was named Satsuma mandarin.
【栄養素・効果効能】
Protein: macromolecule; Structural proteins make up the body, and functional proteins are proteins involved in digestion, transportation, and chemical reactions. Digestive enzymes such as pepsin(aspartic endopeptidase)and trypsin(Endopeptidase & Serine Protease), which are cut by digestive enzymes and decomposed into small peptides and amino acids, absorbed and digested finely, are also made from amino acids.
脂質 ; It has important roles such as being used as an energy source, becoming a component of cell membranes, organs, and nerves, and assisting the transport of vitamins. It keeps a person's body temperature, moisturizes and glitters the skin, helps normal hormones work, and has an active function. Women, in particular, can be detrimental to beauty and health and need some lipids for beautiful skin and hair.  However, if the intake is too high, it will be stored as fat.
炭水化物; It is a compound of carbon(Ca)and hydrogen(H), and is divided into sugar, which is taken into the body as food and used as an energy source, and dietary fiber, which cannot be digested by digestive enzymes in the body.
ビタミンA: C20H30O; Retinol activity equivalent (μgRAE) = retinol (μg) + 1/12 × β-carotene (μg) + 1/24 x α-carotene (μg) + 1/24 × β-cryptoxanthin (μg) + 1/24 × other provitamins A carotenoid (μg).
Lutein: C40H56O2; As an antioxidant, it is expected to have the effect of suppressing active oxygen that causes aging of the eyes, absorbing harmful light, and protecting the eyes. In addition to the eyes, the human body is found in the skin, breast tissue, breast milk, cervix, and brain.
βカロテン: C40H56; Converted to vitamin A in the body as needed.Carotenoids that are abundant in green and yellow vegetables. It is important for maintaining the health of skin and mucous membranes and for photostimulatory response, and promotes cell proliferation.
ビタミンB1; Decarbonization in the ketoglutarate dehydrogenase reaction: Coenzyme; Form of thiamine pyrophosphate.
B2; The form of flavin adenine dinucleotide as a cofactor for the α-ketoglutarate dehydrogenase complex and succinate dehydrogenase.
B6; Pyridoxine(C8H11NO3), Pyridoxal(C8H9NO3), Pyridoxiamine(C8H12N2O2); Coenzyme for protein, lipid and carbohydrate metabolism: It acts as a coenzyme(Pyridoxal phosphate)for metabolism of bioactive amines, which is a neurotransmitter, and as a hormone regulator: Helps keep nerves and skin healthy, fight infections, keep blood sugar levels normal, produce red blood cells, and some enzymes work properly.
パントテン酸(Cofactor fused with active carboxylic acid residues such as Acyl coa and succinyl-coa: Coenzyme A(Cysteamine): C21H36P3N7O16S)
ナイアシン(The form of nicotinamide adenine dinucleotide as a coenzyme of isocitrate dehydrogenase, α-ketotoglutarate dehydrogenase, malate dehydrogenase.)
ビオチン(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid: C10H16N2O3S): ビタミンH; It is a colorless acicular crystal that is stable to neutral, acidic, alkaline, oxygen, and light, but weak to heat. It is released from proteins in food by biotinidase(dominant gene)secreted by the pancreas. It translocates into the blood and binds to biotinidase, a transport protein synthesized in the liver.
葉酸; ビタミンM(2S)-2-[(4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid: C19H19N7O6; Pteridine(C6H4N4)with para-aminobenzoic acid; PABA(C7H7NO2)and another or more glutamic acids. Most exist in the “Polyglutamic acid type” (A combination of multiple glutamic acids). I heard that it is absorbed from the epithelial cells of the small intestine after being converted to the “Monoglutamic acid type” (A form in which one glutamic acid is bound) by digestive enzymes in the digestive tract. It is soluble in acids and alkalis, but hardly soluble in pure water or ethanol, and tends to be insoluble in acetone(C3H6O), Diethyl ether((C2H5)2O), Chloroform(CHCl3), and Benzene(C6H6). In the polyglutamic acid type folate, sugar and protein are released and released in the cooking and processing of foods and in the gastric acid environment. It is decomposed into monoglutamic acid-type folic acid by an enzyme in the small intestinal mucosa and then absorbed into the cells of the small intestine. I heard that it is converted to 5-methyltetrahydrofolic acid by the enzyme(small intestinal epithelial cell). It is transported to the liver via the portal vein, and 50% of the whole body seems to accumulate. It is converted again and transferred to bile, which is reabsorbed from the digestive tract and supplied to tissues for transfer. It is required to return homocysteine, a risk factor for arteriosclerosis, to methionine, etc.
ビタミンC: C6H8O6; Discovered as a Skorbut preventive factor by Royal Navy doctor James Lind in 1753. It removes rust from water-soluble parts of the body, such as blood and the crystalline lens of the eye, and also restores tired vitamin E. It is absorbed mainly from the small intestine as it is without being digested by the stomach. It is then carried in the blood, stored and dispersed throughout the body. It is characterized by its “antioxidant effect”, which inhales, captures a small amount of active oxygen obtained, and detoxifies it. Excessive growth damages DNA or Protein and reduces cell function.
ビタミンE: C29H50O2; It is divided into a total of eight compounds, four tocopherols(In nature, α, β, γ, δ.)and four tocotrienols. It is absorbed into the body from the intestinal tract via the lymphatic vessels together with lipids, and has a very strong antioxidant effect. Protects unsaturated fatty acids and other fat-soluble components that make up biological membranes from oxidative damage: Included in the phospholipid bilayer of cell membranes. It suppresses the production of lipid peroxide, keeps blood vessels healthy, and suppresses the oxidation of LDL(Bad cholesterol)cholesterol in the blood. You will not have hypervitaminosis with a normal diet, as you tend not to have cumulative actions in your body.
β-cryptoxanthin: Provitamin A:C40H56O: Ester body, carotenoid. It forms mixed micelles with bile acids, fatty acids, cholesterol, etc., and is passively diffused and absorbed by small intestinal epithelial cells.Move to liver with chylomicron(Lipoprotein particles; 乳糜脂粒). Very low density lipoprotein and “Low-Density Lipoprotein Cholesterol”: To peripheral tissues≒ Ester body.
Violaxanthin: (1S,4S,6R)-1-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4S,6R)-4-Hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,2,6-trimethyl-7-oxabicyclo[4.1.0] heptan-4-ol; C40H56O4: The gene expression balance is clear, which makes it difficult to accumulate BCR(Caricaxanthin)and facilitates the accumulation of more metabolized VIO(Carotenoid). It is considered as a precursor of a plant hormone called “abscisic acid(C15H20O4)” that promotes leaf fall.
ペクチン: methyl ester: J.Braconnot,1825(Rf): Galacturonic acid: carboxyl group: -C(=O)OH
セルロース:(C6H10O5)n; The main component of plant cell sell stones and plant fibers, and the most abundant carbohydrate on earth.
ヘミセルロース(Amyloid): Discovered by E. Schulze in 1891. The name of the polysaccharide extracted with alkali after extracting Pectin from cell wall carbohydrates. Xyloglucan(Angiospermae): With 1,4-β-D-glucan as the main chain, the α-D-xylose residue binds to the O-6 position of the D-glucose residue of 75%. It is distributed throughout the cell wall including the middle lobe, and I hear that it is hydrogen-bonded to cellulose. Tendency to exist as a storage polysaccharide in seeds.
リグニン: Sphingomonas paucimobilis SYK-6: bacterium: Mineralization; Effective resistance to decay and feeding damage.
ビタミンP: ヘスペリジン; flavonoid: C28H34O15: polyphenol; Glycotransfer works in cooperation with vitamin C to regulate the permeability of the capillary membrane so that it does not become too permeable.
ルチン; C27H30O16: β-rutinose((2R,3S,4S,5S)-6-[ [(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxane-2,3,4,5-tetrol; C12H22O10)bound to quercetin. The E-rutin group significantly increased muscle weight and lean weight in the lower limbs compared to the placebo group that ingested E-rutin-free whey protein-n = 1, isoquercitrin; C21H20O12. Research results increase potential antioxidants in the blood. It protects cells and tissues by suppressing or eliminating the generation of reactive oxygen species, and preserves the normal normality and growth of muscles, etc.
Neohesperidin; C28H34O15
シネフリン: 4-[1-hydroxy-2-(methylamino)ethyl]phenol: C9H13NO2; Used in various slimming natural health products as an alternative to the pharmaceutical ingredient ephedrine. It has effects on heart rate and blood pressure, and both pharmacological effects tend to be significantly enhanced by caffeine. From the identified risk.
オーラプテン: auraptene,7-geranyloxycoumarin: C19H22O3
テルペノイド: Aldehyde,carboxylic acid: C5: IPP, DMAPP: C10, C15, C20: prenyltransferase
ナリンギン: flavanone: C27H32O14; A glycoside in which a sugar called Neo hesperidos is bound to naringenin. When hydrolyzed with the degrading enzyme naringinase, it changes to naringenin without bitterness, so it is often used for fruit juice processing.
Apigenin; C15H10O5: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one: Suppression of mRNA splicing(Processing received after transcription-RNA polymerase ii)Transcription factor -By suppressing the expression of ets-2, the activity of microglia(小膠細胞)can be increased. Binds to the SF3B1 factor in spliceosomes.
クエン酸: C(OH)(CH2COOH)2COOH: C6H8O7; When energy is taken up by the living body, it decomposes through various processes to become a substance called acetyl-coa (active acetic acid), which binds to Oxaloacetic acid(C4H4O5). Later, it transforms into seven types of acids and returns to citric acid. TCA cycle: A substance called “ATP (adenosine triphosphate(C10H16N5O13P3))” that acts as an energy source for cells in the body. Effective against lactic acid, which is the source of stiff shoulders and muscle fatigue.
ブドウ糖: C6H12O6: D-グルコース; Known as a component of cellulose, starch and glycogen. D-glucose(Dextrose, an organic compound.)and pure crystalline monosaccharides produced after the starch is completely hydrolyzed. It is divided into water-containing water containing molecular water of crystallization and anhydrous water containing nothing.
酒石酸: 2,3-dihydroxy butanedioic acid:(CH(OH)COOH)2: L-(+)-Tartaric acid: It is known as a crystalline organic acid obtained by oxidizing and enzymatically decomposing maleic acid(HOOC–CH=CH–COOH: Chain unsaturated dicarboxylic acid)or fumaric acid(HOOC–CH=CH–COOH: C4H4O4: -2-ブテン二酸: Alpha hydroxy acid). 
リンゴ酸: HOOC-CH(OH)-CH2-COOH: C4H6O5; 2-hydroxybutanedioic acid; It is known as an organic acid obtained by synthesizing fumaric acid or reducing glucose. Dicarboxylic acid, in the role of an intermediate in the TCA cycle: Alpha hydroxy acid. 
Kaempferol; C15H10O6
(+)カテキン: C15H14O6; Flavonoids of polyphenols. Derived from the dark brown “catechu” taken from the Acacia Mill. / Acacia (Fabaceae) trees that grow in India.There are research cases that eliminate infectivity by adhering to protruding proteins on the surface such as influenza virus.
イソロイシン(C6H13NO2:2-アミノ-3-メチルペンタン酸); Hydrophobic amino acid(BCCA). The role of promoting the uptake of blood glucose into skeletal muscle without an increase in blood sugar concentration. It works to suppress gluconeogenesis(A pathway that slowly reverses glycolysis from lactic acid, pyruvic acid, amino acid, propionic acid, etc. to produce D-glucose.)in the liver and to oxidatively utilize glucose. A zwitterionic compound having a leucine structural isomer and a sec-butyl group (-ch (ch3) ch2ch3) in the side chain.
ロイシン(C6H13NO2: 2-Amino-4-methylpentanoic acid); Activator of mTOR: mammallian Target Of Rapamycin(Atypical serine-threonine kinases present in two types of complexes: It senses nutrient sources such as glucose and amino acid, and plays a role of regulators in cell proliferation, metabolism, and survival.): There are insulin, IGF-1 (insulin-like growth factor 1: insulin-like growth factors 1), Testosterone, Nitric oxide, Muscle Contraction etc. An important factor that promotes protein synthesis(BCCA).
リシン(リジン: C6H14N2O2: 2,6-diaminohexanoic acid); It is known as a synthetic raw material for carnitine(C7H15NO3: Derivative)required for fat burning.In the human body, we also hear examples of promotion of glucose metabolism and its relationship with calcium absorption. L-Lysine Hydrochloride: Mol fileKCF fileDB search(HCl: hydrochloric acid).
(含硫)メチオニン(C5H11NO2S: 2-amino-4-(methylthio)butanoic acid); It is a sulfur-containing amino acid containing sulfur and is converted into glutathione(C10H17N3O6S)and taurine(C2H7NO3S)in the body. It is also known as a biosynthetic raw material for carnitine involved in fat burning. Tendency to be metabolized in a series of reactions called carbon metabolism. Using methionine and ATP synthase as substrates, S-adenosylmethionine synthase catalyzes the biosynthesis of S-adenosylmethionine(C15H22N6O5S+): Protein methylation.
シスチン( C6H12N2O4S2: 2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid); The role of stabilizing the structure of Proteins. It is one of the sulfur-containing amino acids(The composition of Glutathione-SH(C10H17N3O6S), which is important for detoxification and antioxidant activity.)containing sulfur and has a unique aroma. It converts methionine to Cystathionine(C7H14N2O4S: A catalyst for β-synthase from Homocysteine(C4H9NO2S: 2-Amino-4-sulfanylbutanoic acid)and Serine.)in the human body. It is famous as a sulfur-containing amino acid in which two molecules of cysteine ​​are bound.
(芳香族)フェニルアラニン( C9H11NO2: 2-Amino-3-phenylpropanoic acid); In the brain, the role of Synthesizing Neurotransmitter Norepinephrine(C8H11NO3: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol; Monoamine(A chemical structure in which an amino group is connected to an aromatic ring by two carbon chains.))and Dopamine(C8H11NO2: Monoamine neurotransmitter). It is also known as a raw material for Tyrosine(C9H11NO3: 4-hydroxyphenylalanine; Protein production synthesis). Important for accelerating the amyloid assembly process.Adrenaline(Adrenal medulla): Epinephrine(C9H13NO3), Produced by neurons and released as adrenal medulla hormones and neurotransmitters.
チロシン(C9H11NO3: 2-Amino-3-(4-hydroxyphenyl) propanoic acid); Synthesized by hydroxylation of phenylalanine. When the aromatics are further hydroxylated, L-dopa(C9H11NO4: L-3,4-dihydroxyphenylalanine: (S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid.It is converted to L-Dopa by tyrosine hydroxidase and to dopamine(Nerve cells in a specific area of ​​brain, which is the final product.)by decarboxylase. The neurotransmitter catecholamines (noradrenaline: norepinephrine(C8H11NO3), adrenaline(C9H13NO3): Mainly adrenal medulla(副腎髄質)cells can be metabolized, etc.) are produced from L-Dopa.)is produced. When oxidized by tyrosinase, the intermediate L-Dopa is immediately oxidized and converted to dopachrome(C9H7NO4). It is further polymerized by the action of enzymes and converted to melanin. It is a dark brown pigment and is widely distributed in animal tissues such as skin, hair and iris. I hear that it has a role to absorb excess sunlight. A disease in which tyrosinase is congenitally deficient is known as oculocutaneous disease (albino: Mutant individuals who cannot synthesize photosynthetic pigments: 先天性白皮症) etc.
トレオニン(スレオニン: C4H9NO3: 2-Amino-3-hydroxybutanoic acid): A zwitterionic compound having an Amino group (-NH2) and a carboxyl group (-COOH) and a hydroxyethyl group in the side chain. There are two diastereomers, but only the (2S, 3R) form is called L-threonine(Since it has two optically active centers, four isomers have been identified.). It has been suggested that it may compete with alanine, Branched Chain Amino Acids, phenylalanine, serine, tryptophan, tyrosine etc. I hear that it is the newest in history.
トリプトファン(C11H12N2O2: 2-Amino-3-(1H-indol-3-yl)propanoic acid): A raw material for Nicotinic acid:C6H5NO2 (Niacin: Vitamin B3) in the human body and Serotonin(It is deeply related to important human functions such as mental (stress) and sleep; Endorphin), a neurotransmitter involved in sedation and sleep-inducing action in the brain. Operate the sodium and potassium pumps to discharge the sodium incorporated into the conjugate with glutamic acid. When glutamate and lactic acid are taken up by nerve cells, the most important nerve, the glutamate nerve, begins to move. Glial cells(Oligodendrocytes(希突起膠細胞)that make myelin sheaths(髄鞘)to increase nerve conduction velocity, microglia(小膠細胞)that are responsible for central nervous system immunity, etc. Featured “astrocytes”(Glial fibrillary acidic protein Immunohistochemistry): kallikrein-related peptidase 7:(KLK7): Serine Protease(Proteolytic enzyme with serine group): To elucidate the generation mechanism of neuroglioma.)take up glucose and activate glutamatergic nerves.
バリン(C5H11NO2,SMILES: CC(C)[C@@H](C(=O)O)N): Energy is metabolized in muscle tissue and is involved in growth.Branched Chain Amino Acids(BCAA: Similar to leucine and isoleucine): Expected to adjust the nitrogen balance in blood and improve liver function.
ヒスチジン(C6H9N3O2: 2-Amino-3-(1H-imidazol-4-yl)propanoic acid: It is said to have the effect of suppressing oxidative stress (ischaemia reperfusion), and there are cases of action such as increased insulin secretion. When neonatal screening is abnormal and when amino acid acid metabolism disorder is presumed: I heard that an increase in a specific concentration is a powerful clue to the diagnosis. In the nutritional disorder called cardiac cachexia seen in Chronic congestive heart failure, etc., aromatic amino acids increase and branched chain amino acids and histidine decrease.Since it is abundant in “hemoglobin(Proteins present in red blood cells)”, there is a risk of anemia if it is insufficient. In some cases, it was suggested that the anti-obesity effect was attenuated by “proline(Pyrrolidine-2-carboxylic acid)”.
アルギニン(C6H14N4O2: (S)-2-Amino-5-guanidinopentanoic acid); Expected to help the body produce energy, increase growth hormone secretion, build muscle, and improve male function.Promotes fat metabolism to strengthen muscle tissue and promote height growth. TCA cycle: Adenosine Triphosphate(C10H16N5O13P3), It enhances the function of the urea cycle in the liver and promotes the recovery of brain fatigue quickly. Ammonia(NH3)inhibits its function, but ingestion promotes detoxification. Expected to be effective as part of the Natural Moisturizing Factor(NMF)of the stratum corneum.
アラニン(C3H7NO2: 2-Aminopropanoic acid); It is a synthetic raw material for sugar and has the energy generation function of the living body. The action of secreting the hormone Glucagon(Peptide hormone: 29 amino acid;In the Liver, it activates protein kinase a through binding to specific receptors and cyclic adenosine monophosphate (AMP: cAMP-dependent protein kinase (Protein kinase A); Protein kinase(Phosphorylating enzyme)) production., which is secreted when blood sugar concentration is low and promotes the breakdown of glycogen(C6H10O5)n: Discovered as a liver component by Mr. Claude Bernard in Burgundy, France in 1856.
アスパラギン酸(C4H7NO4: Aminosuccinic acid, asparagic acid; The role of increasing the absorption of K and Mg and decomposing and promoting lactic acid. Located closest to the TCA cycle of the body, which is the place of energy production.)It is located closest to the TCA cycle(Tricarboxylic Acid Cycle: Citric Acid Cycle)of the body, which is the place of energy production. In 1937, German's chemist and doctor Hans Adolf Krebs finds the circuit. England: Received the Nobel Prize in Physiology or Medicine in 1953. Discovery of the Ornithine cycle of Urea synthesis: A cycle that draws out internal combustion.Decomposes fat and lactic acid and converts them into energy(Tricarboxylic Acid Cycle).
グルタミン酸(C5H9NO4: 2-Aminopentanedioic acid: In animals, it can be synthesized from non-essential amino acids, that is, other organic compounds. Discovered by Mr. Karl Heinrich Leopold Ritthausen in 1866 in the acid hydrolyzate of gluten, a wheat protein.It is famous as a raw material for glutathione and GABA (4-aminobutanoic acid). It can be biosynthesized from “2-Oxopentanedioic acid” and “ammonia(NH3)”. It conveys information to nerves by binding to and activating N-methyl-D-aspartic acid (NMDA) -type receptors. D-serine(It has the enzyme serine racemase (SRR) synthesized by Glial cells(It acts to give an energy source to nerve cells in the brain and builds an energy environment: A cell that fills parts of the brain other than nerve cells and supports the functions of nerve cells from various aspects.)located in a specific region of the hippocampus.)regulates stimulus volume. It is believed that the Synapse connection will be strengthened, giving memory and learning. There seems to be a hypothesis that the diseases alzheimer dementia and amyotrophic lateral sclerosis are caused by too much stimulation of the “NMDA receptor”.)
グリシン(Glycocholic: C2H5NO2: Aminoethanoic acid); In the Nerve system, it also functions as an amino acid (Collagen: Protein, Elastin(Elastic fiber), Keratin(△Cystine), Sericin(C30H40N10O16).), which is mainly responsible for inhibitory synaptic transmission between the brain stem and spinal cord. The feature is that there are no stereoisomers(The opposite sex with different three-dimensional directions of atoms in space.)such as D-form and L-form. Not only does it improve the shelf life of food, but it also has a sweet taste and is used as a seasoning. Porphyrins(Porphyra; Hemoglobin as an oxygen carrier in human blood (Erythrocyte) is prominent.) related to the function of carrying oxygen in the blood and creatine(C4H9N3O2; A small amount in the brain.)essential for muscle exercise.
プロリン(C5H9NO2,SMILES: OC(=O)C1CCCN1): The main composition of collagen(Protein; A polymer compound formed by linking (polymerizing) a large number of 21 types of amino acids in a chain: Hydroxyproline(C5H9NO3)), which is abundant in gelatin and animal skins.When stored, aspartic acid tends to decrease and increase. It is high in fruit amino acids.
セリン(C3H7NO3: 2-Amino-3-hydroxypropionic acid); A raw material for Phosphatidylserine(C13H24NO10P,Phospholipid- Signal transduction), a component of cell membranes. It is one of the important moisturizing ingredients to maintain the moisture content of the skin, and can be a raw material for “glycine” that is close to the same ingredient. It is the Natural Moisturizing Factor (NMF: Small molecules such as Amino acids, pyrrolidone carboxylic acids (and their salts), urea, mineral salts, organic acids (and their salts).) of the skin and is the most abundant in amino acid.
エリオシトリン: C27H32O15
ネオエリオシトリン: Eriodictyol(C15H12O6); It is metabolized and absorbed by eriodictyol and found in blood and urine as a glucuronide conjugate.Similarly(homoeriodictyol(C16H14O6), hesperetin(C16H14O6)), the role of inhibitory activity of lipoxygenase (5-LOX and 12-LOX).
ノミリン: TGR5; Transmembrane G protein-coupled Receptor 5: G protein-coupled receptor: C28H34O9 (mw514.57). Bile acids exert anti-obesity and anti-hyperglycemic effects through a G protein- coupled receptor TGR5: Ligand active food ingredient.By binding, it promotes insulin secretion from L-sell. It promotes the secretion of hormone GLP-1. In the living body, it binds to TGR5(G protein-coupled bile acid receptor)of skeletal muscle to increase heat production and exerts an anti-obesity effect through increased energy consumption. The non-sugar moiety that remains after the glycosyl group of the glycoside is replaced by a hydrogen atom: Aglycone; Phytochemical.
リモネン: monoterpene: 1-Methyl-4-(1-methylethenyl)-cyclohexene: C10H16; A terpenoid compound having two double bonds in which two isoprene units (C5 units) are linearly bonded to form a single ring (six-membered ring).
Acridinone,1948: C13H9NO
ポリメトキシフラボノイド類(PMF):ノビレチン(C21H22O8); Long-term potentiation in the hippocampus (LTP): In cognitive impairment such as Alzheimer's disease, synaptic plasticity disorder occurs due to various factors. cAMP response element-binding protein(cAMP-responsive element), I hear that it is cre-dependent transcriptional activity that follows. Expected to have Aβ deposition inhibitory effect and nerve growth factor (NGF) -like effect.
タンゲレチン(C20H20O7)
シネンセチン(C20H20O7); InChI=1S/C20H20O7/c1-22-13-7-6-11(8-15(13)23-2)14-9-12(21)18-16(27-14)10-17(24-3)19(25-4)20(18)26-5/h6-10H,1-5H3,SMILES: COc1ccc(cc1OC)c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1,及び,3,5,6,7,8,3′,4′-ヘプタメトキシフラボン(HMF): Induces the production of brain-derived neurotrophic factor (BDNF; 脳由来神経栄養因子).
γ(gamma)-aminobutyric acid: C4H9NO2; It is responsible for inhibitory synaptic transmission of the rostral central nervous system(Free amino acid series). Glutamic acid by decarboxylation catalyzed by glutamic acid decarboxylase (enzyme: GAD67(GAD1: cytoplasm), GAD65(GAD2: presynaptic terminal)). TCA cycle α-ketoglutaric acid(C5H6O5)to glutamic acid. In some cases, blood pressure lowering effect is achieved by suppressing the release of norepinephrine from pars sympathica: Ion channel type receptor etc.
ポンシリン: (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4, 5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one; C28H34O14: Flavonoid glycoside with the structure of isosakuranetin(C16H14O5)7-O-neoheseridoside. It acts to inhibit osteoclast differentiation and bone loss through down-regulation of NFATc1(Nuclear factor of activated T-cells, cytoplasmic 1: OSCAR,TREM-2,PIR-A etc.)in vitro and in vivo.
ネオポンシリン(ジジミン): (S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; C28H34O14: Suppression of NF-κB(Protein complex; Nuclear factor-kappa B)activation: Prevent vegf Induced angiogenesis in vitro and in vivo.
カリウム: K; It interacts with “Sodium”, which is abundant in extracellular fluid. It works to maintain the osmotic pressure of cells and retain water. After ingestion and absorption in the small intestine, it is transported to tissues throughout the body, most of which is excreted by the kidneys. It is maintained by regulation of reabsorption in the kidney, and the k concentration in blood is maintained between 3.6 and 4.8 meq / l. Together with sodium, it maintains cell osmotic pressure. It works to suppress nerve stimulus transmission, functional regulation of heart and muscle, and intracellular enzyme reaction(I have to add proton transfer equilibrium). I heard that about 200g is contained in the body of an adult, Potassium.
カルシウム: Ca; In the body, the amount in cells and blood is strictly controlled. Tendency to move from bone to blood as needed. About 99% is stored in bone, but also in the blood of cells and muscles. If you don't get the calcium you need, you risk mobilizing large amounts of calcium in your bones and weakening your bones. To maintain normal blood calcium levels, it is necessary to take at least 1000-1500 mg daily. Parathyroid hormone(PTH)and Thyrocalcitonin(Made by the cells of the thyroid gland, hormones have the function of lowering the calcium concentration in the blood by delaying the breakdown of bones.); It is made up of four parathyroid glands behind the thyroid gland in the neck.As the calcium concentration in In blood rises, the amount of hormones produced by the parathyroid glands tends to decrease. It stimulates bones to release calcium into the blood and reduces the amount of calcium excreted by the kidneys into the urine. Increases calcium absorption by stimulating alimentary canal to increase calcium absorption by promoting the activation of vitamin D in the kidneys.
マグネシウム: Mg; Vinegar has been known to solubilize insoluble calcium (Ca) and magnesium (Mg) in food, however, the difference in solubilization ability among various kinds of vinegar has not been investigated. In this study, solubilization of Ca and Mg from coral powder and beef bone powder was compared with several kinds of vinegar. Calcium solubilization was observed to be high in grain vinegar, cider vinegar and wine vinegar, and low in rice vinegar and un-polished rice vinegar. On the other hand, magnesium solubilization was high in rice vinegar, wine vinegar and cider vinegar, and low in grain vinegar and un-polished rice vinegar. Calcium solubilization of coral powder was significantly negatively correlated with the pH of vinegar, while Mg solubilization was not. Comparison of solubilization of Ca in un-polished rice vinegar and acetic acid solution suggested that the phosphorus content was also responsible for solubilization in un-polished vinegar. These results suggest that ingredients in vinegar, as well as acidity and pH, affect solubilization of Ca and Mg from food when cooked with vinegar. Characterization of Solubilization of Insoluble Calcium and Magnesium with Various Kinds of Vinegar,Nakano Central Research Institute, Nakano Vinegar Co., Ltd. and Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University with Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology 45(11), 655-662, 1998-11-15)
ナトリウム: Na; In the adult body, most of it is contained in extracellular fluid outside the cell. Approximately 50 % as salt (sodium chloride), bicarbonate, phosphate. About 40 % is present in the build and is slightly contained in the intracellular fluid. Functions such as osmotic pressure adjustment: Roles such as maintaining the amount of extracellular fluid. Normally, healthy people do not have a deficiency. It is possible to promote the excretion of sodium by taking vegetables and fruits that are high in potassium together. This is because it has been confirmed that taking too much increases the risk of swelling, thirst, high blood pressure, stomach cancer, and esophageal cancer.
リン: P;(Leakage in urine causes symptoms such as hypoproteinemia, decreased renal function, and hyperphosphatemia.)The amount of phosphorus per 1 g of protein contains about 15 mg, and the intake correlates with the protein intake. The role of combining and strengthening bones and teeth. Higher blood phosphate levels tend to make bones brittle. Calcium tends to combine and become coal in other than bones such as blood vessels and tendons.
鉄: Fe; It is attracting attention as one of the world's three major deficient micronutrients along with vitamin A and Iodine(I2; In 1811, Discovered by burning seaweed with potassium carbonate, which is the raw material for potassium nitrate by Bernard Courtois(仏).)Non‐heme iron(Fe)(Included in vegetables, eggs and milk.); By taking it with foods rich in high-quality protein and vitamin C, the absorption rate into the body is improved. Fe shortage of women due to blood loss, a big problem for expectant mother and lactating women whose demand increases. Due to the metabolism of the body, about 1 mg of iron(Fe)is lost in adult men and about 0.8 mg in women per day. Ferritin(A globular protein complex consisting of 24 proteins.)has a role of suppressing deficiency and excess, and is also called stored Fe. About 90% of anemia is iron deficiency, which is deficient in fe, one of the important materials of hemoglobin.
銅: Cu; It has been known for a long time as a trace essential mineral, which is present in the human body at about 80 mg. It binds to proteins and plays a role in catalyzing a wide range of in vivo reactions. Tendency to be mainly present in bone, skeletal muscle and blood. Although it is involved in hematopoietic function as well as Fe, no reports have been heard regarding the adverse effects of chronic overdose, except for some diseases. Monovalent compounds exist as insoluble salts and complex salts. Divalent salts and complex salts are common. It is absorbed from the small and duodenum and transported to the liver through the portal vein. I hear that the lower the intake, the higher the absorption rate, and the higher the intake, the lower the absorption rate.Large amounts of divalent iron and tin ions competitively inhibit the absorption of copper from the gastrointestinal tract. Inborn errors of copper metabolism(Wilson’s disease): Protein binding: Hepatolenticular degeneration.It acts as a Cu enzyme and acts as a catalyst for various reactions such as O2 transport, electron transfer, redox, and O2 addition. Important for Fe metabolism and transport, removal of active oxygen, and metabolism of neurotransmitters. Deficiencies can result from hereditary malabsorption or are acquired, but are not found in the normal life of healthy people. On the other hand, cases of symptoms are given to Babies whose main source of nutrition is low-content milk.Insufficiency may cause anemia, leukopenia, and bone abnormalities that do not respond to Fe administration. In addition, there are decreased immune function, cardiovascular abnormalities, and abnormal cholesterol and glucose metabolism. However, this is less frequent.
亜鉛: Zn; Zinc‐deficiency symptom: A state in which the zinc concentration in the blood is below 80 μg / dL to 130 μg / dL. Dermatitis, stomatitis, alopecia, pressure ulcer due to lack. Loss of appetite, developmental disorders, hypogonadism, susceptibility, dysgeusia, anemia, infertility, etc.Various symptoms occur and tend to improve with zinc supplementation.
マンガン: Mn; Functions as an enzyme activation and a component of metal enzymes.It is a silver-white metal with an atomic number of 25 and an atomic weight of 54.94, and its surface is oxidized in the air. I hear that 12(For a weight of 70 kg)to 20 milligramme is present in the body of an adult. It acts directly with many elements, gradually reacts with water, and is easily dissolved in acids. Absorbed by inhalation, oral or transdermal: Ingested from the diet, it dissolves as divalent by gastric acid and becomes trivalent by the oxidative mechanism of intestinal cells. It is absorbed, transported to the liver through vena portalis, secreted from the bile into the intestinal tract, and mostly excreted as feces. Since absorption competes with Fe, manganese tends to be less likely to be absorbed if the iron content in the diet is high. It is abundant in mitochondria, and is contained in high concentrations in pigmented areas in the body such as the retina, hair, and skin pigmented areas. It suggests specific and non-specific effects on many enzyme activities such as oxidoreductase, hydrolase, dehydrogenase, and transferase. It is also a component of arginine-degrading enzyme, lactate dehydrogenase, and manganese superoxide dismutase (MnSOD). Examples include connective tissue and bone formation, inner ear growth formation, glucose tolerance, fertility, lipid metabolism, growth and involvement in brain function.
【Effect / Efficacy】
抗癌作用: Anti-cancer effect 
抗酸化作用: Antioxidant effect
抗菌作用: Antibacterial effect
抗腫瘍性: Anticancerous
肩こり: Stiff shoulder
腰痛: Lumbago
髪の毛健康: Hair health
風邪予防: Prevention of cold
美肌・美容: Beautiful skin and beauty
老化防止: Prevention from getting older
ダイエット: Diet
むくみ解消: Edema
利尿効果: Diuretic effect
女性ホルモン: Female hormones
妊婦: Expectant mother
貧血: Anemia
疲労回復: Recovery from fatigue
視力維持: Maintaining eyesight
消化促進: Digestion promotion
殺菌効果: Bactericidal effect
骨粗しょう症: Osteoporosis
新陳代謝: Metabolism
ストレス解消: Stress relief
活性酸素抑制: Reactive oxygen species suppression
喉・呼吸器安定: Throat, respiratory stability
皮膚粘膜強化: Skin and mucous membrane strengthening
高血圧: Elevated blood pressure
肥満: Corpulence
生活習慣病: Life style related disease
血中コレステロール緩和: Blood cholesterol relief
コレステロール: Triglycerides 
二日酔い: Overnight drunkenness
心筋梗塞: Heart infarction
脳梗塞: Brain infarction
血栓予防: Thromboprophylaxis
食欲不振: Anorexia
精神安定: Tranquilize
認知機能改善: Cognitive function improvement
胃潰瘍: Gastric ulcer
胃腸障害: Gastrointestinal injury
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